About: GRAFT VERSUS HOST DISEASE AFTER ALLOGENEIC STEM CELL TRANSPLANTATION AND ITS PREDICTION BY PROTEOMIC APPROACHES     Goto   Sponge   NotDistinct   Permalink

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Description
  • Background: Acute graft versus host disease (GvHD) is a frequent complication of allogeneic stem cells transplantation (alloSCT). The rapid diagnosis of acute GvHD following alloSCT is important for optimizing the management of this life-threatening complication. Differentially expressed or excreted polypeptides and proteins have potential for early and accurate diagnosis of GvHD and other complications of allo-SCT. Aims: Search for blood plasma proteins useful as potential biomarkers for early detection of GvHD. Methods: 2-dimensional gel electrophoresis (2-DE) was used for separation of blood plasma proteins. Proteins considered as potential biomarkers for early prediction of GvHD were selected by image analysis. Protein spots with different expression levels were characterized by matrix-assisted laser desorption/ionization - time of flight mass spectrometry (MALDI-TOF-MS) using peptide mass fingerprinting.
  • Background: Acute graft versus host disease (GvHD) is a frequent complication of allogeneic stem cells transplantation (alloSCT). The rapid diagnosis of acute GvHD following alloSCT is important for optimizing the management of this life-threatening complication. Differentially expressed or excreted polypeptides and proteins have potential for early and accurate diagnosis of GvHD and other complications of allo-SCT. Aims: Search for blood plasma proteins useful as potential biomarkers for early detection of GvHD. Methods: 2-dimensional gel electrophoresis (2-DE) was used for separation of blood plasma proteins. Proteins considered as potential biomarkers for early prediction of GvHD were selected by image analysis. Protein spots with different expression levels were characterized by matrix-assisted laser desorption/ionization - time of flight mass spectrometry (MALDI-TOF-MS) using peptide mass fingerprinting. (en)
Title
  • GRAFT VERSUS HOST DISEASE AFTER ALLOGENEIC STEM CELL TRANSPLANTATION AND ITS PREDICTION BY PROTEOMIC APPROACHES
  • GRAFT VERSUS HOST DISEASE AFTER ALLOGENEIC STEM CELL TRANSPLANTATION AND ITS PREDICTION BY PROTEOMIC APPROACHES (en)
skos:prefLabel
  • GRAFT VERSUS HOST DISEASE AFTER ALLOGENEIC STEM CELL TRANSPLANTATION AND ITS PREDICTION BY PROTEOMIC APPROACHES
  • GRAFT VERSUS HOST DISEASE AFTER ALLOGENEIC STEM CELL TRANSPLANTATION AND ITS PREDICTION BY PROTEOMIC APPROACHES (en)
skos:notation
  • RIV/00216224:14310/07:00022291!RIV10-MSM-14310___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(LC06034), S, Z(MSM0021622415)
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 423585
http://linked.open...ai/riv/idVysledku
  • RIV/00216224:14310/07:00022291
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • acute graft-versus-host disease; proteomics; biomarkers (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...ontrolniKodProRIV
  • [FA2330AA1369]
http://linked.open...v/mistoKonaniAkce
  • Vídeň
http://linked.open...i/riv/mistoVydani
  • Itálie
http://linked.open...i/riv/nazevZdroje
  • Hematologica the hematology journal volume 92 (s1 June 2007)
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...iv/tvurceVysledku
  • Konečná, Hana
  • Mayer, Jiří
  • Pospíšilová, Šárka
  • Zdráhal, Zbyněk
  • Šedo, Ondrej
  • Tomancová, Alexandra
http://linked.open...vavai/riv/typAkce
http://linked.open.../riv/zahajeniAkce
http://linked.open...n/vavai/riv/zamer
issn
  • 0390-6078
number of pages
http://purl.org/ne...btex#hasPublisher
  • Typographia PI-ME, Viavientina Pavia Italy
http://localhost/t...ganizacniJednotka
  • 14310
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