About: Semiparametric Estimation of Hazard Function for Cancer Patients

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The main aim of this paper is to model and study the survival of cancer patients. First, a parametric form of hazard function is proposed. This model results from a recent model of cancer cells population dynamics given in the paper Kozusko and Bajzer (Mathematical Biosciences, 2003) and depends on several parameters. The method of estimating such parameters is described as well. On the other hand, the nonparametric methods seem to be appropriate for survival data. Among them, the methods of kernel estimation of hazard functions are very effective ones. But there is a serious difficulty with them, namely the choice of a smoothing parameter. We propose an alternative method for the bandwidth selection based on the aforementioned parametric method. The theory developed is applied to four data sets. The main aim of this paper is to model and study the survival of cancer patients. First, a parametric form of hazard function is proposed. This model results from a recent model of cancer cells population dynamics given in the paper Kozusko and Bajzer (Mathematical Biosciences, 2003) and depends on several parameters. The method of estimating such parameters is described as well. On the other hand, the nonparametric methods seem to be appropriate for survival data. Among them, the methods of kernel estimation of hazard functions are very effective ones. But there is a serious difficulty with them, namely the choice of a smoothing parameter. We propose an alternative method for the bandwidth selection based on the aforementioned parametric method. The theory developed is applied to four data sets. (en)
Title	Semiparametric Estimation of Hazard Function for Cancer Patients Semiparametric Estimation of Hazard Function for Cancer Patients (en)
skos:prefLabel	Semiparametric Estimation of Hazard Function for Cancer Patients Semiparametric Estimation of Hazard Function for Cancer Patients (en)
skos:notation	RIV/00216224:14310/07:00021003!RIV10-MSM-14310___
http://linked.open...avai/riv/aktivita	P
http://linked.open...avai/riv/aktivity	P(GA201/01/0079), P(LC06024)
http://linked.open...iv/cisloPeriodika	3
http://linked.open...vai/riv/dodaniDat	2010
http://linked.open...aciTvurceVysledku	Pospíšil, Zdeněk Zelinka, Jiří Horová, Ivanka
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Přírodovědecká fakulta
http://linked.open...dnocenehoVysledku	449411
http://linked.open...ai/riv/idVysledku	RIV/00216224:14310/07:00021003
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Hazard function; kernel estimation; Gompertzian growth; parameter estimation (en)
http://linked.open.../riv/klicoveSlovo	Hazard function parameter estimation kernel estimation Gompertzian growth
http://linked.open...odStatuVydavatele	CZ - Česká republika
http://linked.open...ontrolniKodProRIV	[2BDE5986BAD6]
http://linked.open...i/riv/nazevZdroje	Sankhya: The Indian Journal of Statistic
http://linked.open...in/vavai/riv/obor	BB
http://linked.open...ichTvurcuVysledku	3 (xsd:int)
http://linked.open...cetTvurcuVysledku	3 (xsd:int)
http://linked.open...vavai/riv/projekt	Jaroslav Hájek Center for Theoretical and Applied Statistics Qualitative theory of solutions of difference equations
http://linked.open...UplatneniVysledku	2007
http://linked.open...v/svazekPeriodika	69
http://linked.open...iv/tvurceVysledku	Pospíšil, Zdeněk Horová, Ivanka Zelinka, Jiří
issn	0972-7671
number of pages	20 (xsd:int)
http://localhost/t...ganizacniJednotka	14310

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