About: Temporal vs. spatial variations in concentrations of compounds with specific modes of action in river sediment samples

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	In numerous studies the contamination of river sediments has been assessed both by chemical analysis and especially by bioassays from single time sampling reflecting just the actual situation. Two year study has been conducted to reveal the spatial and temporal-seasonal variability in the concentrations of commonly studied contaminants, but namely of the chemicals with specific modes of action in river sediments. Along with analysis of known pollutants we have assessed the overall potencies of the sediment extracts for cytotoxicity, dioxin-like, (anti)estrogenic and (anti)androgenic potency. Battery of in vitro bioassays with recombinant yeast and human cell systems was used to evaluate the extracts of sediments from four consequent sampling representing two different seasons. These bioassays show an integrative measure and identify the sites with continuously increased potencies for specific toxicity. In numerous studies the contamination of river sediments has been assessed both by chemical analysis and especially by bioassays from single time sampling reflecting just the actual situation. Two year study has been conducted to reveal the spatial and temporal-seasonal variability in the concentrations of commonly studied contaminants, but namely of the chemicals with specific modes of action in river sediments. Along with analysis of known pollutants we have assessed the overall potencies of the sediment extracts for cytotoxicity, dioxin-like, (anti)estrogenic and (anti)androgenic potency. Battery of in vitro bioassays with recombinant yeast and human cell systems was used to evaluate the extracts of sediments from four consequent sampling representing two different seasons. These bioassays show an integrative measure and identify the sites with continuously increased potencies for specific toxicity. (en)
Title	Temporal vs. spatial variations in concentrations of compounds with specific modes of action in river sediment samples Temporal vs. spatial variations in concentrations of compounds with specific modes of action in river sediment samples (en)
skos:prefLabel	Temporal vs. spatial variations in concentrations of compounds with specific modes of action in river sediment samples Temporal vs. spatial variations in concentrations of compounds with specific modes of action in river sediment samples (en)
skos:notation	RIV/00216224:14310/07:00020383!RIV11-GA0-14310___
http://linked.open...avai/riv/aktivita	P
http://linked.open...avai/riv/aktivity	P(GP525/05/P160)
http://linked.open...vai/riv/dodaniDat	2011
http://linked.open...aciTvurceVysledku	Jálová, Veronika Hilscherová, Klára Štěpánková, Tereza
http://linked.open.../riv/druhVysledku	O - Ostatní výsledky nezařaditelné do žádného z výše uvedených druhů výsledku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Přírodovědecká fakulta
http://linked.open...dnocenehoVysledku	454524
http://linked.open...ai/riv/idVysledku	RIV/00216224:14310/07:00020383
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	in vitro bioassays; (anti)estrogenicity; (anti)androgenicity; TCDD-like activity (en)
http://linked.open.../riv/klicoveSlovo	(anti)androgenicity (anti)estrogenicity TCDD-like activity in vitro bioassays
http://linked.open...ontrolniKodProRIV	[5AC8C3620D96]
http://linked.open...in/vavai/riv/obor	DJ
http://linked.open...ichTvurcuVysledku	3 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...vavai/riv/projekt	In vitro models for study of endocrine disruption - effects of traditional and new types of persistent organic pollutants
http://linked.open...UplatneniVysledku	2007
http://linked.open...iv/tvurceVysledku	Hilscherová, Klára Štěpánková, Tereza Giesy, J. Jálová, Veronika
http://localhost/t...ganizacniJednotka	14310

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