About: Changes of AhR-mediated activity of humic substances after irradiation

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Humic substances (HS) and natural organic matter (NOM) are natural organic compounds ubiquitous in the environment. However, some studies indicate that both HS and NOM can act as xenobiotics, e.g. induce hormone like effects in fish, amphibians and invertebrates. Molecules of these substances contain a number of aromatic rings and conjugated double bonds, the so called chromophores. Irradiation of dissolved HS and NOM can lead to a series of photochemical reactions which can act on these substances itself, or on other substances present in aquatic environment along with HS and NOM such as e.g. xenobiotics. In our previous study, we have found significant interactions of five humic acids (HA) with cytosolic aryl hydrocarbon receptor (AhR) in an in vitro bioassay based on H4IIEluc cells. In the present study, we have studied the changes in AhR mediated activities both of HS and NOM after irradiation that simulated natural solar light. Humic substances (HS) and natural organic matter (NOM) are natural organic compounds ubiquitous in the environment. However, some studies indicate that both HS and NOM can act as xenobiotics, e.g. induce hormone like effects in fish, amphibians and invertebrates. Molecules of these substances contain a number of aromatic rings and conjugated double bonds, the so called chromophores. Irradiation of dissolved HS and NOM can lead to a series of photochemical reactions which can act on these substances itself, or on other substances present in aquatic environment along with HS and NOM such as e.g. xenobiotics. In our previous study, we have found significant interactions of five humic acids (HA) with cytosolic aryl hydrocarbon receptor (AhR) in an in vitro bioassay based on H4IIEluc cells. In the present study, we have studied the changes in AhR mediated activities both of HS and NOM after irradiation that simulated natural solar light. (en)
Title	Changes of AhR-mediated activity of humic substances after irradiation Changes of AhR-mediated activity of humic substances after irradiation (en)
skos:prefLabel	Changes of AhR-mediated activity of humic substances after irradiation Changes of AhR-mediated activity of humic substances after irradiation (en)
skos:notation	RIV/00216224:14310/07:00020354!RIV10-MSM-14310___
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GP525/05/P160), Z(MSM0021622412)
http://linked.open...iv/cisloPeriodika	33
http://linked.open...vai/riv/dodaniDat	2010
http://linked.open...aciTvurceVysledku	Bittner, Michal Hilscherová, Klára
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Přírodovědecká fakulta
http://linked.open...dnocenehoVysledku	413249
http://linked.open...ai/riv/idVysledku	RIV/00216224:14310/07:00020354
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Humic acids; Ah receptor; H4IIE-luc; Absorbance; NOM (en)
http://linked.open.../riv/klicoveSlovo	NOM H4IIE-luc Ah receptor Absorbance Humic acids
http://linked.open...odStatuVydavatele	NL - Nizozemsko
http://linked.open...ontrolniKodProRIV	[372EB20D9845]
http://linked.open...i/riv/nazevZdroje	Environment International
http://linked.open...in/vavai/riv/obor	DN
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	3 (xsd:int)
http://linked.open...vavai/riv/projekt	In vitro models for study of endocrine disruption - effects of traditional and new types of persistent organic pollutants
http://linked.open...UplatneniVysledku	2007
http://linked.open...v/svazekPeriodika	33
http://linked.open...iv/tvurceVysledku	Giesy, John Paul Hilscherová, Klára Bittner, Michal
http://linked.open...ain/vavai/riv/wos	000248273700013
http://linked.open...n/vavai/riv/zamer	Interactions among the chemicals, environment and biological systems and their consequences on the global, regional and local scales (INCHEMBIOL)
issn	0160-4120
number of pages	6 (xsd:int)
http://localhost/t...ganizacniJednotka	14310

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