About: Interference of N-heterocyclic PAHs with signaling of retinoids

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Interference of N-heterocyclic PAHs with signaling of retinoids Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	N-heterocyclic analogs of PAHs (N-PAHs) are as well as homocyclic PAHs important and widespread environmental contaminants. Many of them are carcinogens, mutagens and teratogens. Some results indicate that N-PAHs have higher toxic and genotoxic potencies and bioavailability than PAHs. In this study the interference of N-PAHs with retinoid signaling system was tested. After 24 h exposure most of three, four and five ring PAHs and N-PAHs increased RA activity. Obtained data were statistically analyzed and quantitative-structure activity relationship study was performed. This study was supported by GACR 525/05/P160. N-heterocyclic analogs of PAHs (N-PAHs) are as well as homocyclic PAHs important and widespread environmental contaminants. Many of them are carcinogens, mutagens and teratogens. Some results indicate that N-PAHs have higher toxic and genotoxic potencies and bioavailability than PAHs. In this study the interference of N-PAHs with retinoid signaling system was tested. After 24 h exposure most of three, four and five ring PAHs and N-PAHs increased RA activity. Obtained data were statistically analyzed and quantitative-structure activity relationship study was performed. This study was supported by GACR 525/05/P160. (en)
Title	Interference of N-heterocyclic PAHs with signaling of retinoids Interference of N-heterocyclic PAHs with signaling of retinoids (en)
skos:prefLabel	Interference of N-heterocyclic PAHs with signaling of retinoids Interference of N-heterocyclic PAHs with signaling of retinoids (en)
skos:notation	RIV/00216224:14310/07:00020348!RIV11-GA0-14310___
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GP525/05/P160), Z(MSM0021622412)
http://linked.open...vai/riv/dodaniDat	2011
http://linked.open...aciTvurceVysledku	Beníšek, Martin Bláha, Luděk Pacherník, Jiří Hilscherová, Klára
http://linked.open.../riv/druhVysledku	O - Ostatní výsledky nezařaditelné do žádného z výše uvedených druhů výsledku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Přírodovědecká fakulta
http://linked.open...dnocenehoVysledku	427153
http://linked.open...ai/riv/idVysledku	RIV/00216224:14310/07:00020348
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	retinoid; N-PAHs; in vitro (en)
http://linked.open.../riv/klicoveSlovo	retinoid N-PAHs in vitro
http://linked.open...ontrolniKodProRIV	[F944F6260C66]
http://linked.open...in/vavai/riv/obor	DN
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...vavai/riv/projekt	In vitro models for study of endocrine disruption - effects of traditional and new types of persistent organic pollutants
http://linked.open...UplatneniVysledku	2007
http://linked.open...iv/tvurceVysledku	Bláha, Luděk Hilscherová, Klára Pacherník, Jiří Beníšek, Martin
http://linked.open...n/vavai/riv/zamer	Interactions among the chemicals, environment and biological systems and their consequences on the global, regional and local scales (INCHEMBIOL)
http://localhost/t...ganizacniJednotka	14310

Faceted Search & Find service v1.16.118 as of Jun 21 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 58 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software