About: Nestin as a biomarker of transformed cells in solid tumors and tumor cell lines

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Nestin as a biomarker of transformed cells in solid tumors and tumor cell lines Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Nestin (intermediate filament class VI protein) is expressed in proliferating neuroepithelium during the development of mammalian CNS as well as in human and rodent neural stem cells and cell lines. In the adult CNS, nestin is detectable only in stem cells of the subventricular zone and partly in the choroid plexus. Our study was aimed at the nestin expression in cell lines derived from different types of solid tumors both in children and adults. Using immunodetection methods, nestin expression has been shown in tissue sections and cell lines derived from neuroectodermal tumors (glioblastoma multiforme, neuroblastoma), as well as from malignant fibrose histiocytoma and osteosarcoma. We also focused on the subcellular localization of nestin in the cell lines as described above. Our results brought the direct evidence of the nestin occurrence in cell nucleus in cell lines derived from neuroblastoma and glioblastoma multiforme. Nestin (intermediate filament class VI protein) is expressed in proliferating neuroepithelium during the development of mammalian CNS as well as in human and rodent neural stem cells and cell lines. In the adult CNS, nestin is detectable only in stem cells of the subventricular zone and partly in the choroid plexus. Our study was aimed at the nestin expression in cell lines derived from different types of solid tumors both in children and adults. Using immunodetection methods, nestin expression has been shown in tissue sections and cell lines derived from neuroectodermal tumors (glioblastoma multiforme, neuroblastoma), as well as from malignant fibrose histiocytoma and osteosarcoma. We also focused on the subcellular localization of nestin in the cell lines as described above. Our results brought the direct evidence of the nestin occurrence in cell nucleus in cell lines derived from neuroblastoma and glioblastoma multiforme. (en)
Title	Nestin as a biomarker of transformed cells in solid tumors and tumor cell lines Nestin as a biomarker of transformed cells in solid tumors and tumor cell lines (en)
skos:prefLabel	Nestin as a biomarker of transformed cells in solid tumors and tumor cell lines Nestin as a biomarker of transformed cells in solid tumors and tumor cell lines (en)
skos:notation	RIV/00216224:14310/07:00019133!RIV10-MZ0-14310___
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(NR9125), Z(MSM0021622415)
http://linked.open...vai/riv/dodaniDat	2010
http://linked.open...aciTvurceVysledku	Veselská, Renata Štěrba, Jaroslav Loja, Tomáš Zitterbart, Karel Chlapek, Petr Zambo, Iva Hermanová, Markéta
http://linked.open.../riv/druhVysledku	O - Ostatní výsledky nezařaditelné do žádného z výše uvedených druhů výsledku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Přírodovědecká fakulta
http://linked.open...dnocenehoVysledku	436929
http://linked.open...ai/riv/idVysledku	RIV/00216224:14310/07:00019133
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	nestin; intermediate filaments; glioblastoma multiforme; osteosarcoma; neuroblastoma; medulloblastoma; malignant fibrose histiocytoma (en)
http://linked.open.../riv/klicoveSlovo	osteosarcoma nestin glioblastoma multiforme intermediate filaments medulloblastoma neuroblastoma malignant fibrose histiocytoma
http://linked.open...ontrolniKodProRIV	[E8E3A83615E8]
http://linked.open...in/vavai/riv/obor	FD
http://linked.open...ichTvurcuVysledku	7 (xsd:int)
http://linked.open...cetTvurcuVysledku	7 (xsd:int)
http://linked.open...vavai/riv/projekt	Importance of molecular cytogenetic markers for diagnosis and prediction of embryonal childhood tumors.
http://linked.open...UplatneniVysledku	2007
http://linked.open...iv/tvurceVysledku	Chlapek, Petr Hermanová, Markéta Loja, Tomáš Veselská, Renata Zitterbart, Karel Zambo, Iva Štěrba, Jaroslav
http://linked.open...n/vavai/riv/zamer	Molecular basis of cell and tissue regulations
http://localhost/t...ganizacniJednotka	14310

Faceted Search & Find service v1.16.118 as of Jun 21 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 48 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software