About: Intracellular trafficking and proteolysis of the auxin efflux facilitator PIN2 in Arabidopsis is proteasomedependent and involved in root gravitropism

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About: Intracellular trafficking and proteolysis of the auxin efflux facilitator PIN2 in Arabidopsis is proteasomedependent and involved in root gravitropism Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Root gravitropism describes the orientation of root growth along the gravity vector and is mediated by differential cell elongation in the root meristem. This response requires the coordinated, asymmetric distribution of the phytohormone auxin within the root meristem, and depends on the concerted activities of PIN proteins and AUX1 members of the auxin transport pathway. Here, we show that intracellular trafficking and proteasome activity combine to control PIN2 degradation during root gravitropism. Following gravi-stimulation, proteasome-dependent variations in PIN2 localization and degradation at the upper and lower sides of the root result in asymmetric distribution of PIN2. Ubiquitination of PIN2 occurs in a proteasome-dependent manner, indicating that the proteasome is involved in the control of PIN2 turnover. Stabilization of PIN2 affects its abundance and distribution, and leads to defects in auxin distribution and gravitropic responses. Root gravitropism describes the orientation of root growth along the gravity vector and is mediated by differential cell elongation in the root meristem. This response requires the coordinated, asymmetric distribution of the phytohormone auxin within the root meristem, and depends on the concerted activities of PIN proteins and AUX1 members of the auxin transport pathway. Here, we show that intracellular trafficking and proteasome activity combine to control PIN2 degradation during root gravitropism. Following gravi-stimulation, proteasome-dependent variations in PIN2 localization and degradation at the upper and lower sides of the root result in asymmetric distribution of PIN2. Ubiquitination of PIN2 occurs in a proteasome-dependent manner, indicating that the proteasome is involved in the control of PIN2 turnover. Stabilization of PIN2 affects its abundance and distribution, and leads to defects in auxin distribution and gravitropic responses. (en)
Title	Intracellular trafficking and proteolysis of the auxin efflux facilitator PIN2 in Arabidopsis is proteasomedependent and involved in root gravitropism Intracellular trafficking and proteolysis of the auxin efflux facilitator PIN2 in Arabidopsis is proteasomedependent and involved in root gravitropism (en)
skos:prefLabel	Intracellular trafficking and proteolysis of the auxin efflux facilitator PIN2 in Arabidopsis is proteasomedependent and involved in root gravitropism Intracellular trafficking and proteolysis of the auxin efflux facilitator PIN2 in Arabidopsis is proteasomedependent and involved in root gravitropism (en)
skos:notation	RIV/00216224:14310/06:00016659!RIV10-MSM-14310___
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(LC06034), Z(MSM0021622415)
http://linked.open...iv/cisloPeriodika	8
http://linked.open...vai/riv/dodaniDat	2010
http://linked.open...aciTvurceVysledku	Friml, Jiří
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Přírodovědecká fakulta
http://linked.open...dnocenehoVysledku	480240
http://linked.open...ai/riv/idVysledku	RIV/00216224:14310/06:00016659
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	auxin transport; PIN proteins; Arabidopsis; gravitropism (en)
http://linked.open.../riv/klicoveSlovo	gravitropism auxin transport Arabidopsis PIN proteins
http://linked.open...odStatuVydavatele	CZ - Česká republika
http://linked.open...ontrolniKodProRIV	[A2CC16FA332F]
http://linked.open...i/riv/nazevZdroje	Nature Cell Biology
http://linked.open...in/vavai/riv/obor	EB
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	9 (xsd:int)
http://linked.open...vavai/riv/projekt	Regulation of morphogenesis of plant cells and organs
http://linked.open...UplatneniVysledku	2006
http://linked.open...v/svazekPeriodika	2006
http://linked.open...iv/tvurceVysledku	Friml, Jiří Abas, L. Paciorek, T. Luschnig, C. Benjamins, R. Malenica, N. Moulinier-Anzola, J. C. Sieberer, T. Wisniewska, J.
http://linked.open...n/vavai/riv/zamer	Molecular basis of cell and tissue regulations
issn	1465-7392
number of pages	7 (xsd:int)
http://localhost/t...ganizacniJednotka	14310

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