About: Attomole voltammetric determination of metallothionein

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Number of authors have concerned with electrochemical analysis of metallothionein. Recently new electroanalytical techniques enabling determination of MT at picomole level has been suggested. The aim of the presented work was to show advantages and disadvantages of the different electrochemical procedures, which are commonly used for the detection of MT(i) cyclic voltammetry, (ii) differential pulse voltammetry, and (iii) Brdicka reaction. Primarily we aimed on improvement of the mentioned techniques. Using of reducing agent (tris(2-carboxyethyl)phosphine) and combination of the mentioned method with adsorptive transfer stripping technique (AdTS) were the main improvements of the voltammetric method. The detection limits of metallothionein measured by cyclic voltammetry (CV), differential pulse voltammetry (DPV) and DPV Brdicka reaction were 0.5 pmol, 4 fmol and 10 amol, respectively. Number of authors have concerned with electrochemical analysis of metallothionein. Recently new electroanalytical techniques enabling determination of MT at picomole level has been suggested. The aim of the presented work was to show advantages and disadvantages of the different electrochemical procedures, which are commonly used for the detection of MT(i) cyclic voltammetry, (ii) differential pulse voltammetry, and (iii) Brdicka reaction. Primarily we aimed on improvement of the mentioned techniques. Using of reducing agent (tris(2-carboxyethyl)phosphine) and combination of the mentioned method with adsorptive transfer stripping technique (AdTS) were the main improvements of the voltammetric method. The detection limits of metallothionein measured by cyclic voltammetry (CV), differential pulse voltammetry (DPV) and DPV Brdicka reaction were 0.5 pmol, 4 fmol and 10 amol, respectively. (en)
Title	Attomole voltammetric determination of metallothionein Attomole voltammetric determination of metallothionein (en)
skos:prefLabel	Attomole voltammetric determination of metallothionein Attomole voltammetric determination of metallothionein (en)
skos:notation	RIV/00216224:14310/06:00015758!RIV10-MSM-14310___
http://linked.open...avai/riv/aktivita	P V Z
http://linked.open...avai/riv/aktivity	P(GP525/04/P132), V, Z(AV0Z50040507), Z(MSM0021622412)
http://linked.open...iv/cisloPeriodika	24
http://linked.open...vai/riv/dodaniDat	2010
http://linked.open...aciTvurceVysledku	Jelen, František Trnková, Libuše Adam, Vojtěch Kizek, René Mikelová, Radka Potěšil, David
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Přírodovědecká fakulta
http://linked.open...dnocenehoVysledku	466309
http://linked.open...ai/riv/idVysledku	RIV/00216224:14310/06:00015758
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Metallothionein; Mercury electrode; Differential pulse voltammetry; Cyclic voltammetry; Brdicka reaction; Adsorptive transfer stripping technique; Reducing agent; Tris(2-carboxyethyl)phosphine; Lead poisoning; Human blood serum (en)
http://linked.open.../riv/klicoveSlovo	Metallothionein Differential pulse voltammetry Mercury electrode Lead poisoning Reducing agent Tris(2-carboxyethyl)phosphine Adsorptive transfer stripping technique Cyclic voltammetry Brdicka reaction Human blood serum
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[A89A1831BA46]
http://linked.open...i/riv/nazevZdroje	Electrochimica Acta
http://linked.open...in/vavai/riv/obor	CG
http://linked.open...ichTvurcuVysledku	6 (xsd:int)
http://linked.open...cetTvurcuVysledku	10 (xsd:int)
http://linked.open...vavai/riv/projekt	Study of protection mechanisms for stress-induced by heavy metals
http://linked.open...UplatneniVysledku	2006
http://linked.open...v/svazekPeriodika	51
http://linked.open...iv/tvurceVysledku	Adam, Vojtěch Kizek, René Průša, Richard Trnková, Libuše Blaštík, Ondřej Jelen, František Petrlová, Jitka Kukačka, Jiří Mikelová, Radka Potěšil, David
http://linked.open...n/vavai/riv/zamer	Biophysics of dynamic structures and functions of biological systems Interactions among the chemicals, environment and biological systems and their consequences on the global, regional and local scales (INCHEMBIOL)
issn	0013-4686
number of pages	8 (xsd:int)
http://localhost/t...ganizacniJednotka	14310

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