About: Activation of AH-receptor by humic substances

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Humic substances (HS) are natural compounds formed as products of decay of organic matter. They are ubiquitous in the environment, particularly in soil and aquatic ecosystems. There are generally three basic groups of humic substances: Humic acids (HA), fulvic acids and humins. Until recently, HS were generally considered to be inert in the ecosystems and the research was focused mainly on the sorption of metals and organic contaminants on HS. However, in last years the scientific concern shifted also to toxicological effects of pure humic substances. Recent studies showed that they are able to elicit hormone-like effects and changes in biochemical parameters in fish, crustaceans and nematodes. Moreover, HS seem to play an important role in progression of endemic Kashin-Beck and Blackfoot diseases. In our study, we investigated interactions between HA and Ah-receptor (receptor connected with so-called dioxin-like toxicity; AhR). Humic substances (HS) are natural compounds formed as products of decay of organic matter. They are ubiquitous in the environment, particularly in soil and aquatic ecosystems. There are generally three basic groups of humic substances: Humic acids (HA), fulvic acids and humins. Until recently, HS were generally considered to be inert in the ecosystems and the research was focused mainly on the sorption of metals and organic contaminants on HS. However, in last years the scientific concern shifted also to toxicological effects of pure humic substances. Recent studies showed that they are able to elicit hormone-like effects and changes in biochemical parameters in fish, crustaceans and nematodes. Moreover, HS seem to play an important role in progression of endemic Kashin-Beck and Blackfoot diseases. In our study, we investigated interactions between HA and Ah-receptor (receptor connected with so-called dioxin-like toxicity; AhR). (en)
Title	Activation of AH-receptor by humic substances Activation of AH-receptor by humic substances (en)
skos:prefLabel	Activation of AH-receptor by humic substances Activation of AH-receptor by humic substances (en)
skos:notation	RIV/00216224:14310/05:00014614!RIV10-MSM-14310___
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GP525/05/P160), Z(MSM0021622412)
http://linked.open...vai/riv/dodaniDat	2010
http://linked.open...aciTvurceVysledku	Bittner, Michal Bláha, Luděk Holoubek, Ivan Hilscherová, Klára Janošek, Jaroslav
http://linked.open.../riv/druhVysledku	D - Článek ve sborníku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Přírodovědecká fakulta
http://linked.open...dnocenehoVysledku	511297
http://linked.open...ai/riv/idVysledku	RIV/00216224:14310/05:00014614
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Humic substances; dioxin-like activity (en)
http://linked.open.../riv/klicoveSlovo	Humic substances dioxin-like activity
http://linked.open...ontrolniKodProRIV	[6833B134E042]
http://linked.open...v/mistoKonaniAkce	Toila. Estonsko
http://linked.open...i/riv/mistoVydani	Tallinn, Estonsko
http://linked.open...i/riv/nazevZdroje	Joint Conference of Scandinavian Society of Cell Toxicology and Estonian Society of Toxicology
http://linked.open...in/vavai/riv/obor	DN
http://linked.open...ichTvurcuVysledku	5 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...vavai/riv/projekt	In vitro models for study of endocrine disruption - effects of traditional and new types of persistent organic pollutants
http://linked.open...UplatneniVysledku	2005
http://linked.open...iv/tvurceVysledku	Bláha, Luděk Giesy, John Paul Hilscherová, Klára Holoubek, Ivan Bittner, Michal Janošek, Jaroslav
http://linked.open...vavai/riv/typAkce	WRD - Světová
http://linked.open.../riv/zahajeniAkce	2005-10-20 (xsd:date)
http://linked.open...n/vavai/riv/zamer	Interactions among the chemicals, environment and biological systems and their consequences on the global, regional and local scales (INCHEMBIOL)
number of pages	1 (xsd:int)
http://purl.org/ne...btex#hasPublisher	ETS-SSCT
https://schema.org/isbn	9949-13-297-5
http://localhost/t...ganizacniJednotka	14310

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