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  • A hazard function depending on three interpretable parameters is proposed. The expression of it originates in two assumptions - the hazard depends on growth of cancer cells and cancer cell population follows the Gompertz growth model. Then a method for estimation of the parameters is developed and applicability of it is illustrated on simulated data. The described approach is applied to five sets of cancer patients survival data and it is compared with a different one - kernel estimation of the hazard function.
  • A hazard function depending on three interpretable parameters is proposed. The expression of it originates in two assumptions - the hazard depends on growth of cancer cells and cancer cell population follows the Gompertz growth model. Then a method for estimation of the parameters is developed and applicability of it is illustrated on simulated data. The described approach is applied to five sets of cancer patients survival data and it is compared with a different one - kernel estimation of the hazard function. (en)
Title
  • A parametric estimation of hazard function for cancer patients
  • A parametric estimation of hazard function for cancer patients (en)
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  • A parametric estimation of hazard function for cancer patients
  • A parametric estimation of hazard function for cancer patients (en)
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  • RIV/00216224:14310/05:00012565!RIV10-GA0-14310___
http://linked.open...avai/riv/aktivita
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  • P(GA201/01/0079)
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  • 511017
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  • RIV/00216224:14310/05:00012565
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  • Hazard function; parametric estimation; cancer (en)
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  • [9AFD1F460760]
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  • Pospíšil, Zdeněk
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  • 14310
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