About: Pyrazolopyrimidines as Cyclin Dependent Kinase Inhibitors

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The title pyrazolo[1,5-a]pyrimidines [I; Q = SO2NR6R7, CONR6R7, CO2R7; R2 = (un)substituted alkyl, alkynyl, alkynylalkyl, cycloalkyl, CF3, CO2R6, aryl, arylalkyl, heteroarylalkyl, heterocyclyl, etc., wherein aryl is optionally substituted; R3 = H, halogen, NR5R6, CONR5R6, CO2R4, each (un)substituted alkyl, alkynyl, cycloalkyl, aryl, arylalkyl, heterocyclyl, heterocyclylalkyl, heteroaryl, or heteroarylalkyl, etc.; R4 = H, halo, alkyl; R5 = H, alkyl; R6 = H, each (un)substituted alkyl, aryl, arylalkyl, cycloalkyl, heterocyclyl, heterocyclylalkyl, heteroaryl, or heteroarylalkyl; R7 = each (un)substituted alkyl, cycloalkyl, aryl, heteroaryl, arylalkyl, or heteroarylalkyl; or R5 and R6 in the moiety -NR5R6, may be joined together to form an (un)substituted cycloalkyl or heterocyclyl] or pharmaceutically acceptable salts or solvates thereof are prepd. In its many embodiments, the present invention also provides methods of prepg. such compds., pharmaceutical compns. contg. one or more such compds. The title pyrazolo[1,5-a]pyrimidines [I; Q = SO2NR6R7, CONR6R7, CO2R7; R2 = (un)substituted alkyl, alkynyl, alkynylalkyl, cycloalkyl, CF3, CO2R6, aryl, arylalkyl, heteroarylalkyl, heterocyclyl, etc., wherein aryl is optionally substituted; R3 = H, halogen, NR5R6, CONR5R6, CO2R4, each (un)substituted alkyl, alkynyl, cycloalkyl, aryl, arylalkyl, heterocyclyl, heterocyclylalkyl, heteroaryl, or heteroarylalkyl, etc.; R4 = H, halo, alkyl; R5 = H, alkyl; R6 = H, each (un)substituted alkyl, aryl, arylalkyl, cycloalkyl, heterocyclyl, heterocyclylalkyl, heteroaryl, or heteroarylalkyl; R7 = each (un)substituted alkyl, cycloalkyl, aryl, heteroaryl, arylalkyl, or heteroarylalkyl; or R5 and R6 in the moiety -NR5R6, may be joined together to form an (un)substituted cycloalkyl or heterocyclyl] or pharmaceutically acceptable salts or solvates thereof are prepd. In its many embodiments, the present invention also provides methods of prepg. such compds., pharmaceutical compns. contg. one or more such compds. (en)
Title	Pyrazolopyrimidines as Cyclin Dependent Kinase Inhibitors Pyrazolopyrimidines as Cyclin Dependent Kinase Inhibitors (en)
skos:prefLabel	Pyrazolopyrimidines as Cyclin Dependent Kinase Inhibitors Pyrazolopyrimidines as Cyclin Dependent Kinase Inhibitors (en)
skos:notation	RIV/00216224:14310/04:00035997!RIV10-MSM-14310___
http://linked.open...tracePatentuVzoru	2003-09-03 (xsd:date)
http://linked.open...avai/riv/aktivita	N
http://linked.open...avai/riv/aktivity	N
http://linked.open...cisloPatentuVzoru	WO 2004/022062 A1
http://linked.open...eleniPatentuVzoru	2004-03-18 (xsd:date)
http://linked.open...vai/riv/dodaniDat	2010
http://linked.open...aciTvurceVysledku	Paruch, Kamil
http://linked.open.../riv/druhVysledku	P - Patent
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Přírodovědecká fakulta
http://linked.open...dnocenehoVysledku	583273
http://linked.open...ai/riv/idVysledku	RIV/00216224:14310/04:00035997
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	cyclin dependent kinase; inhibitor; pyrazolopyrimidine (en)
http://linked.open.../riv/klicoveSlovo	pyrazolopyrimidine cyclin dependent kinase inhibitor
http://linked.open...ontrolniKodProRIV	[BC93421B4746]
http://linked.open.../licencniPoplatek	A - Poskytovatel licence na výsledek požaduje licenční poplatek
http://linked.open...ydaniPatentuVzoru	USA
http://linked.open...atelePatentuVzoru	World Intellectual Property Organization
http://linked.open...in/vavai/riv/obor	FD
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	12 (xsd:int)
http://linked.open...UplatneniVysledku	2004
http://linked.open...ydaniPatentuVzoru	US - Spojené státy americké
http://linked.open...iv/tvurceVysledku	Dwyer, Michael Guzi, Timothy Paruch, Kamil Doll, Ronald James, Ray Knutson, Chad McKittrick, Brian Park, Haengsoon Girijavallabhan, Viyyoor Dillard, Lawrence He, Zhen Tran, Vinh
http://linked.open...mniOchranaPatentu	B - USTPO (Úřad pro patenty a ochranné známky USA)
http://linked.open...avai/riv/vlastnik	Schering Plough; Pharmacopeia
http://linked.open...itiJinymSubjektem	A - Nabytí licence je nutné vždy
http://linked.open...uzitiPatentuVzoru	A - Pouze udělený nebo využívaný pouze vlastníkem
http://linked.open...stnikPatentuVzoru	Schering Plough; Pharmacopeia
http://localhost/t...ganizacniJednotka	14310

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