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rdf:type
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Description
| - Elektroktroanalytické stanovení oligonukleotidu d(GCGAAGC) (cs)
- Hairpins (or hairpin-like structures) may play a major role in expansion events of triplet repeat expansion diseases (X syndrome, Huntington s disease, Friedreich s ataxia). The d(GCGAAGC) fragment has been found in the replication origins of phage fX 174 and herpes simplex virus, in a promoter region of an E.coli heat-shock gene, and in rRNA genes. The paper deals with the application of electrochemical methods to the determination of the DNA heptamer - d(GCGAAGC) which forms very stable hairpin structure in aqueous solutions. On mercury electrodes this hairpin provides voltammetric reduction signals of adenine and cytosine, and oxidation signals of guanine. Both signals have been studied by cyclic voltammetry (CV), linear sweep voltammetry (LSV), and elimination voltammetry with linear scan (EVLS) in dependence on pH, accumulation time, scan rate, and loop sequences. The EVLS in combination with the adsorptive stripping was employed to the determination of the detection limit (LD) of this mini-hairp
- Hairpins (or hairpin-like structures) may play a major role in expansion events of triplet repeat expansion diseases (X syndrome, Huntington s disease, Friedreich s ataxia). The d(GCGAAGC) fragment has been found in the replication origins of phage fX 174 and herpes simplex virus, in a promoter region of an E.coli heat-shock gene, and in rRNA genes. The paper deals with the application of electrochemical methods to the determination of the DNA heptamer - d(GCGAAGC) which forms very stable hairpin structure in aqueous solutions. On mercury electrodes this hairpin provides voltammetric reduction signals of adenine and cytosine, and oxidation signals of guanine. Both signals have been studied by cyclic voltammetry (CV), linear sweep voltammetry (LSV), and elimination voltammetry with linear scan (EVLS) in dependence on pH, accumulation time, scan rate, and loop sequences. The EVLS in combination with the adsorptive stripping was employed to the determination of the detection limit (LD) of this mini-hairp (en)
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Title
| - Elektroktroanalytické stanovení oligonukleotidu d(GCGAAGC) (cs)
- Electroanalytical determination of d(GCGAAGC) hairpin
- Electroanalytical determination of d(GCGAAGC) hairpin (en)
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skos:prefLabel
| - Elektroktroanalytické stanovení oligonukleotidu d(GCGAAGC) (cs)
- Electroanalytical determination of d(GCGAAGC) hairpin
- Electroanalytical determination of d(GCGAAGC) hairpin (en)
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skos:notation
| - RIV/00216224:14310/04:00011178!RIV08-AV0-14310___
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http://linked.open.../vavai/riv/strany
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
| - P(GA203/02/0422), P(IAA1163201)
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/00216224:14310/04:00011178
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - The DNA heptamer d(GCGAAGC); mini-hairpins; Linear sweep voltammetry (LSV); Cyclic voltammetry (CV); Elimination voltammetry with linear scan (EVLS); Hanging mercury drop electrode (HMDE); adsorptive stripping procedure (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...vavai/riv/projekt
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Trnková, Libuše
- Postbieglová, Irena
- Holík, Miroslav
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issn
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number of pages
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http://localhost/t...ganizacniJednotka
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