About: Glycosyltransferasa LgtC: MD Simulace     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
Description
  • Prvni MD simulace na LgtC (cs)
  • First molecular dynamics (MD) simulations, performed on complex LgtC with manganese ion and donor substrate (UDP-Gal), were recently reported [3]. Since the amino acid sequence in the crystal structure is shorter than that in natural enzyme (29 residues in C-terminal domain missing), the artificial carboxyl group on C-terminal (Leu282) was considered in that study. In this work, we have run several MD simulations of systems with blocked (electro-neutral Nmethylamide.) and native Leu282 and have compared the results. We have also focused our attention on analysis of behavior of this enzyme under physiological and non-physiological conditions during the MD simulations. Even if physiological conditions (0.1 M NaCl) are more natural for proteins, they are not frequently used in computational methods as the presence of relatively high concentration of ions may cause problems. We will show differences in behaviour of the protein with blocked and native C-terminal carboxyl group, and of system under physiolo
  • First molecular dynamics (MD) simulations, performed on complex LgtC with manganese ion and donor substrate (UDP-Gal), were recently reported [3]. Since the amino acid sequence in the crystal structure is shorter than that in natural enzyme (29 residues in C-terminal domain missing), the artificial carboxyl group on C-terminal (Leu282) was considered in that study. In this work, we have run several MD simulations of systems with blocked (electro-neutral Nmethylamide.) and native Leu282 and have compared the results. We have also focused our attention on analysis of behavior of this enzyme under physiological and non-physiological conditions during the MD simulations. Even if physiological conditions (0.1 M NaCl) are more natural for proteins, they are not frequently used in computational methods as the presence of relatively high concentration of ions may cause problems. We will show differences in behaviour of the protein with blocked and native C-terminal carboxyl group, and of system under physiolo (en)
Title
  • Glycosyltransferasa LgtC: MD Simulace
  • Glycosyltransferasa LgtC: MD Simulace (en)
  • Glycosyltransferase LgtC: MD Simulations under Physiological and Non-physiological Conditions (cs)
skos:prefLabel
  • Glycosyltransferasa LgtC: MD Simulace
  • Glycosyltransferasa LgtC: MD Simulace (en)
  • Glycosyltransferase LgtC: MD Simulations under Physiological and Non-physiological Conditions (cs)
skos:notation
  • RIV/00216224:14310/04:00010546!RIV/2005/MSM/143105/N
http://linked.open.../vavai/riv/strany
  • P388
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(LN00A016)
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 565654
http://linked.open...ai/riv/idVysledku
  • RIV/00216224:14310/04:00010546
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • Molecular dynamics,galactosyltransferase,physiological conditions (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...ontrolniKodProRIV
  • [B5785D14C78F]
http://linked.open...v/mistoKonaniAkce
  • Glasgow, Great Britain
http://linked.open...i/riv/mistoVydani
  • Glasgow
http://linked.open...i/riv/nazevZdroje
  • 22nd International Carbohydrate Symposium
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...iv/tvurceVysledku
  • Imberty, Anne
  • Koča, Jaroslav
  • Kulhánek, Petr
  • Šnajdrová, Lenka
http://linked.open...vavai/riv/typAkce
http://linked.open.../riv/zahajeniAkce
number of pages
http://purl.org/ne...btex#hasPublisher
  • International Carbohydrate Organisation
http://localhost/t...ganizacniJednotka
  • 14310
Faceted Search & Find service v1.16.118 as of Jun 21 2024


Alternative Linked Data Documents: ODE     Content Formats:   [cxml] [csv]     RDF   [text] [turtle] [ld+json] [rdf+json] [rdf+xml]     ODATA   [atom+xml] [odata+json]     Microdata   [microdata+json] [html]    About   
This material is Open Knowledge   W3C Semantic Web Technology [RDF Data] Valid XHTML + RDFa
OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 67 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software