About: Trichomonas vaginalis initiator binding protein, IBP39, contains a novel DNA binding motif     Goto   Sponge   NotDistinct   Permalink

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Description
  • This study focuses on the detailed characterization of the only transcription factor identified in the human pathogen Trichomonas vaginalis, the IBP39 protein. Here we show the nuclear localization of IBP39. In addition, we map the DNA binding domain. It resides near the N-terminus of the protein, between amino acids 45 and 71. The residues 66-70 (KMKKK) are critical for DNA binding. This is the first DNA binding domain to be mapped in the only transcription factor in this parasite to date.
  • This study focuses on the detailed characterization of the only transcription factor identified in the human pathogen Trichomonas vaginalis, the IBP39 protein. Here we show the nuclear localization of IBP39. In addition, we map the DNA binding domain. It resides near the N-terminus of the protein, between amino acids 45 and 71. The residues 66-70 (KMKKK) are critical for DNA binding. This is the first DNA binding domain to be mapped in the only transcription factor in this parasite to date. (en)
Title
  • Trichomonas vaginalis initiator binding protein, IBP39, contains a novel DNA binding motif
  • Trichomonas vaginalis initiator binding protein, IBP39, contains a novel DNA binding motif (en)
skos:prefLabel
  • Trichomonas vaginalis initiator binding protein, IBP39, contains a novel DNA binding motif
  • Trichomonas vaginalis initiator binding protein, IBP39, contains a novel DNA binding motif (en)
skos:notation
  • RIV/00216224:14310/03:00036236!RIV10-MSM-14310___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • V
http://linked.open...iv/cisloPeriodika
  • 2
http://linked.open...vai/riv/dodaniDat
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http://linked.open...iv/duvernostUdaju
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  • 631572
http://linked.open...ai/riv/idVysledku
  • RIV/00216224:14310/03:00036236
http://linked.open...riv/jazykVysledku
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  • Trichomonas; initiator binding protein; transcription; protozoa (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [450851E1DDE1]
http://linked.open...i/riv/nazevZdroje
  • Molecular and Biochemical Parasitology
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
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http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 130
http://linked.open...iv/tvurceVysledku
  • Vaňáčová, Štěpánka
  • Johnson, Patricia J.
  • Liston, D. R.
  • Lau, A.O.T.
http://linked.open...ain/vavai/riv/wos
  • 000185273100016
issn
  • 0166-6851
number of pages
http://localhost/t...ganizacniJednotka
  • 14310
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