About: Use of artificial neural networks for the evaluation UV-Vis spectra of adenine and cytosine in mixtures

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About: Use of artificial neural networks for the evaluation UV-Vis spectra of adenine and cytosine in mixtures Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Recently we have demonstrated advantages of artificial neural networks (ANNs) for quantification of nucleic acid bases mixtures from overlapping voltammetric signals. In this work ANNs were applied to analyze adenine-cytosine mixtures from UV-Vis spectra. Spectra of these compounds are highly similar (lambda max 261 and 270nm, respectively) and common spectral approaches of analysis are failing. The optimal ANN architecture, able to model the system, was established. Software of ANNs method was from TRAJAN 6 program. Using the suitable experimental design with soft ANN modeling adenine - cytosine mixtures can be quantified with an excellent precision (less than 1%). Generally, ANNs open many possibilities for the analysis of mixtures of biologically important substances with very overlapped signals, even without the explicit knowledge of their behavior. Recently we have demonstrated advantages of artificial neural networks (ANNs) for quantification of nucleic acid bases mixtures from overlapping voltammetric signals. In this work ANNs were applied to analyze adenine-cytosine mixtures from UV-Vis spectra. Spectra of these compounds are highly similar (lambda max 261 and 270nm, respectively) and common spectral approaches of analysis are failing. The optimal ANN architecture, able to model the system, was established. Software of ANNs method was from TRAJAN 6 program. Using the suitable experimental design with soft ANN modeling adenine - cytosine mixtures can be quantified with an excellent precision (less than 1%). Generally, ANNs open many possibilities for the analysis of mixtures of biologically important substances with very overlapped signals, even without the explicit knowledge of their behavior. (en)
Title	Use of artificial neural networks for the evaluation UV-Vis spectra of adenine and cytosine in mixtures Use of artificial neural networks for the evaluation UV-Vis spectra of adenine and cytosine in mixtures (en)
skos:prefLabel	Use of artificial neural networks for the evaluation UV-Vis spectra of adenine and cytosine in mixtures Use of artificial neural networks for the evaluation UV-Vis spectra of adenine and cytosine in mixtures (en)
skos:notation	RIV/00216224:14310/02:00006278!RIV/2003/AV0/143103/N
http://linked.open.../vavai/riv/strany	482
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(IAA1163201), Z(MSM 143100011)
http://linked.open...vai/riv/dodaniDat	2003
http://linked.open...aciTvurceVysledku	Havel, Josef Topinková, Jana Trnková, Libuše
http://linked.open.../riv/druhVysledku	D - Článek ve sborníku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Přírodovědecká fakulta
http://linked.open...dnocenehoVysledku	668046
http://linked.open...ai/riv/idVysledku	RIV/00216224:14310/02:00006278
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	adenine;cytosine;UV-Vis spectra;artificial neural networks;TRAJAN 6;chemometrics (en)
http://linked.open.../riv/klicoveSlovo	artificial neural networks TRAJAN 6 chemometrics adenine cytosine UV-Vis spectra
http://linked.open...ontrolniKodProRIV	[8D50BFA4808C]
http://linked.open...v/mistoKonaniAkce	30.6. - 4.7. 2002, Brno, Česká republika
http://linked.open...i/riv/mistoVydani	Praha
http://linked.open...i/riv/nazevZdroje	Chemické listy
http://linked.open...in/vavai/riv/obor	CB
http://linked.open...ichTvurcuVysledku	3 (xsd:int)
http://linked.open...cetTvurcuVysledku	3 (xsd:int)
http://linked.open...ocetUcastnikuAkce	0 (xsd:int)
http://linked.open...nichUcastnikuAkce	0 (xsd:int)
http://linked.open...vavai/riv/projekt	Application of adsorptive transfer and elemination techniques in oligonucleotides and nucleic acids analysis.
http://linked.open...UplatneniVysledku	2002
http://linked.open...iv/tvurceVysledku	Havel, Josef Trnková, Libuše Topinková, Jana
http://linked.open...vavai/riv/typAkce	EUR - Evropská
http://linked.open.../riv/zahajeniAkce	2002-01-01 (xsd:date)
http://linked.open...n/vavai/riv/zamer	http://linked.opendata.cz/resource/domain/vavai/zamer/MSM%20143100011
issn	0009-2770
number of pages	1 (xsd:int)
http://purl.org/ne...btex#hasPublisher	Česká společnost chemická
http://localhost/t...ganizacniJednotka	14310

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