About: The Association Study of DRD2, ACE and AGT Gene Polymorphisms and Metamphetamine Dependence

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About: The Association Study of DRD2, ACE and AGT Gene Polymorphisms and Metamphetamine Dependence Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	We investigated for the first time the association between the metamphetamine dependence and TaqI A polymorphism of the dopamine receptor D2 gene, I/D ACE polymorphism and M235T polymorphism of the angiotensinogen gene (AGT) in 93 unrelated metamphetamine dependent subjects and 131 controls. Our results did not prove any association of the TaqI A polymorphism of the DRD2 gene, I/D polymorphism of ACE gene and M235T polymorphism of AGT gene with the metamphetamine dependence in Caucasians of Czech origin, however, a statistically significant difference in I allele frequency between male control and female control groups for the I/D ACE polymorphism (p<0.03) was found. We investigated for the first time the association between the metamphetamine dependence and TaqI A polymorphism of the dopamine receptor D2 gene, I/D ACE polymorphism and M235T polymorphism of the angiotensinogen gene (AGT) in 93 unrelated metamphetamine dependent subjects and 131 controls. Our results did not prove any association of the TaqI A polymorphism of the DRD2 gene, I/D polymorphism of ACE gene and M235T polymorphism of AGT gene with the metamphetamine dependence in Caucasians of Czech origin, however, a statistically significant difference in I allele frequency between male control and female control groups for the I/D ACE polymorphism (p<0.03) was found. (en) We investigated for the first time the association between the metamphetamine dependence and TaqI A polymorphism of the dopamine receptor D2 gene, I/D ACE polymorphism and M235T polymorphism of the angiotensinogen gene (AGT) in 93 unrelated metamphetamine dependent subjects and 131 controls. Our results did not prove any association of the TaqI A polymorphism of the DRD2 gene, I/D polymorphism of ACE gene and M235T polymorphism of AGT gene with the metamphetamine dependence in Caucasians of Czech origin, however, a statistically significant difference in I allele frequency between male control and female control groups for the I/D ACE polymorphism (p<0.03) was found. (cs)
Title	The Association Study of DRD2, ACE and AGT Gene Polymorphisms and Metamphetamine Dependence The Association Study of DRD2, ACE and AGT Gene Polymorphisms and Metamphetamine Dependence (en) The Association Study of DRD2, ACE and AGT Gene Polymorphisms and Metamphetamine Dependence (cs)
skos:prefLabel	The Association Study of DRD2, ACE and AGT Gene Polymorphisms and Metamphetamine Dependence The Association Study of DRD2, ACE and AGT Gene Polymorphisms and Metamphetamine Dependence (en) The Association Study of DRD2, ACE and AGT Gene Polymorphisms and Metamphetamine Dependence (cs)
skos:notation	RIV/00216224:14310/01:00005069!RIV08-MSM-14310___
http://linked.open.../vavai/riv/strany	43
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(NF5991), P(NF6520), Z(MSM 111100001), Z(MSM 141100002)
http://linked.open...iv/cisloPeriodika	1
http://linked.open...vai/riv/dodaniDat	2008
http://linked.open...aciTvurceVysledku	Šerý, Omar Vymětalová, Veronika Zvolský, Petr
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Přírodovědecká fakulta
http://linked.open...dnocenehoVysledku	673960
http://linked.open...ai/riv/idVysledku	RIV/00216224:14310/01:00005069
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	TaqI A polymorphism; DRD2; ACE; M235T; Angiotensinogen; Metamphetamine dependence (en)
http://linked.open.../riv/klicoveSlovo	ACE Angiotensinogen M235T Metamphetamine dependence TaqI A polymorphism DRD2
http://linked.open...odStatuVydavatele	CZ - Česká republika
http://linked.open...ontrolniKodProRIV	[F6A84AE193DC]
http://linked.open...i/riv/nazevZdroje	Physiological Research
http://linked.open...in/vavai/riv/obor	ED
http://linked.open...ichTvurcuVysledku	3 (xsd:int)
http://linked.open...cetTvurcuVysledku	3 (xsd:int)
http://linked.open...vavai/riv/projekt	Genetic study of alcohol dependence : detection of the association between candidate gene polymorphisms and alcoholism. Clinical and molecular-biological correlates of attention deficit hyperactivity disorder in children
http://linked.open...UplatneniVysledku	2001
http://linked.open...v/svazekPeriodika	50
http://linked.open...iv/tvurceVysledku	Vymětalová, Veronika Zvolský, Petr Šerý, Omar
http://linked.open...n/vavai/riv/zamer	http://linked.opendata.cz/resource/domain/vavai/zamer/MSM%20111100001 http://linked.opendata.cz/resource/domain/vavai/zamer/MSM%20141100002
issn	0862-8408
number of pages	8 (xsd:int)
http://localhost/t...ganizacniJednotka	14310

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