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  • The merging of silicon microfabrication techniques with surface functionalization biochemistry offers new exciting opportunities in developing microscopic biomedical analysis devices with unique characteristics. Micro-mechanical transducers for chemical and biosensing applications represent one possibility. Microcantilevers can transduce a chemical signal into a mechanical motion with high sensitivity. In this review we summarize how cantilever-based sensors can be operated, and their working principle is presented in few selected biosensing experiments which have been performed recently in our groups in the study of biotin-streptavidin and antigen-antibody interactions, and specific surface charge development of organic molecules. We also discuss the advantages of this novel technique as well as its potentials.
  • The merging of silicon microfabrication techniques with surface functionalization biochemistry offers new exciting opportunities in developing microscopic biomedical analysis devices with unique characteristics. Micro-mechanical transducers for chemical and biosensing applications represent one possibility. Microcantilevers can transduce a chemical signal into a mechanical motion with high sensitivity. In this review we summarize how cantilever-based sensors can be operated, and their working principle is presented in few selected biosensing experiments which have been performed recently in our groups in the study of biotin-streptavidin and antigen-antibody interactions, and specific surface charge development of organic molecules. We also discuss the advantages of this novel technique as well as its potentials. (en)
Title
  • Micromechanical cantilever-based biosensors
  • Micromechanical cantilever-based biosensors (en)
skos:prefLabel
  • Micromechanical cantilever-based biosensors
  • Micromechanical cantilever-based biosensors (en)
skos:notation
  • RIV/00216224:14310/01:00004850!RIV/2002/GA0/143102/N
http://linked.open.../vavai/riv/strany
  • 115
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(GA203/96/0070)
http://linked.open...iv/cisloPeriodika
  • 2
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 686894
http://linked.open...ai/riv/idVysledku
  • RIV/00216224:14310/01:00004850
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • microcantilever; immunosensor; albumin; immobilization; biosensor (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • NL - Nizozemsko
http://linked.open...ontrolniKodProRIV
  • [AC719DF05FAF]
http://linked.open...i/riv/nazevZdroje
  • Sensors and Actuators B Chemical
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...ocetUcastnikuAkce
http://linked.open...nichUcastnikuAkce
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 79
http://linked.open...iv/tvurceVysledku
  • Skládal, Petr
  • Raiteri, Roberto
  • Butt, Hans-Jurgen
  • Grattarola, Massimo
issn
  • 0925-4005
number of pages
http://localhost/t...ganizacniJednotka
  • 14310
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