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rdf:type
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Description
| - Associations among five gene polymorphism interactions and clinically manifested psoriasis were studied. All studied gene polymorphisms (endothelin-1-ET-1, transporters associated with antigen processing-TAP1, tumor necrosis factor beta-TNF beta, angiotensin I converting enzyme-ACE, advanced glycosylation end product-specific receptor- RAGE) were analyzed for their possible participation in the MHC class I cell surface antigen presentation to CD8+ T-cells. In psoriatic patients (n=153), the disequilibrium was found for coincidence of TNF beta with TAPl-333 ( P=0.016) as well as with TAP1-637 ( P=0.035). TNF beta was in disequilibrium with (ACE) polymorphism (P=0.036). ACE was observed to be in tight disequilibrium with TAP1-333 (p= 0.009) but not with TAP1-637 (P=0.133). The borderline significance of disequilibrium was found for ET-1 and RAGE gene polymorphisms (P=0.07).
- Associations among five gene polymorphism interactions and clinically manifested psoriasis were studied. All studied gene polymorphisms (endothelin-1-ET-1, transporters associated with antigen processing-TAP1, tumor necrosis factor beta-TNF beta, angiotensin I converting enzyme-ACE, advanced glycosylation end product-specific receptor- RAGE) were analyzed for their possible participation in the MHC class I cell surface antigen presentation to CD8+ T-cells. In psoriatic patients (n=153), the disequilibrium was found for coincidence of TNF beta with TAPl-333 ( P=0.016) as well as with TAP1-637 ( P=0.035). TNF beta was in disequilibrium with (ACE) polymorphism (P=0.036). ACE was observed to be in tight disequilibrium with TAP1-333 (p= 0.009) but not with TAP1-637 (P=0.133). The borderline significance of disequilibrium was found for ET-1 and RAGE gene polymorphisms (P=0.07). (en)
- Associations among five gene polymorphism interactions and clinically manifested psoriasis were studied. All studied gene polymorphisms (endothelin-1-ET-1, transporters associated with antigen processing-TAP1, tumor necrosis factor beta-TNF beta, angiotensin I converting enzyme-ACE, advanced glycosylation end product-specific receptor- RAGE) were analyzed for their possible participation in the MHC class I cell surface antigen presentation to CD8+ T-cells. In psoriatic patients (n=153), the disequilibrium was found for coincidence of TNF beta with TAPl-333 ( P=0.016) as well as with TAP1-637 ( P=0.035). TNF beta was in disequilibrium with (ACE) polymorphism (P=0.036). ACE was observed to be in tight disequilibrium with TAP1-333 (p= 0.009) but not with TAP1-637 (P=0.133). The borderline significance of disequilibrium was found for ET-1 and RAGE gene polymorphisms (P=0.07). (cs)
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Title
| - Interaction of five gene polymorphism at psoriasis
- Interaction of five gene polymorphism at psoriasis (en)
- Interaction of five gene polymorphism at psoriasis (cs)
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skos:prefLabel
| - Interaction of five gene polymorphism at psoriasis
- Interaction of five gene polymorphism at psoriasis (en)
- Interaction of five gene polymorphism at psoriasis (cs)
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skos:notation
| - RIV/00216224:14110/99:00002134!RIV09-GA0-14110___
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
| - P(GA306/93/2192), P(GA306/96/0099), P(VS96097), Z(MSM 141100002)
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/00216224:14110/99:00002134
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - gene; polymorphism; TAP; TNF; endothelin; ACE (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
| - US - Spojené státy americké
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
| - The Journal of Investigative Dermatology
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...vavai/riv/projekt
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Izakovičová-Hollá, Lydie
- Vašků, Anna
- Kaňková, Kateřina
- Vašků, Vladimír
- Semrádová, Věra
- Znojil, Vladimír
- Vácha, Jiří
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http://linked.open...ain/vavai/riv/wos
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http://linked.open...n/vavai/riv/zamer
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issn
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number of pages
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http://localhost/t...ganizacniJednotka
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