About: Pelvic lymphadenectomy improves survival in patients with cervical cancer with low-volume disease in the sentinel node: A retrospective multicenter cohort study

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About: Pelvic lymphadenectomy improves survival in patients with cervical cancer with low-volume disease in the sentinel node: A retrospective multicenter cohort study Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Objective: In this study, we aimed to describe the value of pelvic lymph node dissection (LND) after sentinel lymph node (SN) biopsy in early-stage cervical cancer. Methods: We performed a retrospective multicenter cohort study in 8 gynecological oncology departments. In total, 645 women with International Federation of Gynecology and Obstetrics stage IA to IIB cervical cancer of squamous, adeno, or adenosquamous histologic type who underwent SN biopsy followed by pelvic LND were enrolled in this study. Radioisotope tracers and blue dyewere used to localize the sentinel node, and pathologic ultrastaging was performed. Results: Among the patients with low-volume disease (micrometastases and isolated tumor cells) in the sentinel node, the overall survivalwas significantly better (P = 0.046) ifmore than 16 non-SNs were removed. No such significant difference in survivalwas detected in patients with negative or macrometastatic sentinel nodes. Objective: In this study, we aimed to describe the value of pelvic lymph node dissection (LND) after sentinel lymph node (SN) biopsy in early-stage cervical cancer. Methods: We performed a retrospective multicenter cohort study in 8 gynecological oncology departments. In total, 645 women with International Federation of Gynecology and Obstetrics stage IA to IIB cervical cancer of squamous, adeno, or adenosquamous histologic type who underwent SN biopsy followed by pelvic LND were enrolled in this study. Radioisotope tracers and blue dyewere used to localize the sentinel node, and pathologic ultrastaging was performed. Results: Among the patients with low-volume disease (micrometastases and isolated tumor cells) in the sentinel node, the overall survivalwas significantly better (P = 0.046) ifmore than 16 non-SNs were removed. No such significant difference in survivalwas detected in patients with negative or macrometastatic sentinel nodes. (en)
Title	Pelvic lymphadenectomy improves survival in patients with cervical cancer with low-volume disease in the sentinel node: A retrospective multicenter cohort study Pelvic lymphadenectomy improves survival in patients with cervical cancer with low-volume disease in the sentinel node: A retrospective multicenter cohort study (en)
skos:prefLabel	Pelvic lymphadenectomy improves survival in patients with cervical cancer with low-volume disease in the sentinel node: A retrospective multicenter cohort study Pelvic lymphadenectomy improves survival in patients with cervical cancer with low-volume disease in the sentinel node: A retrospective multicenter cohort study (en)
skos:notation	RIV/00216224:14110/14:00075682!RIV15-MSM-14110___
http://linked.open...avai/riv/aktivita	I N
http://linked.open...avai/riv/aktivity	I, N
http://linked.open...iv/cisloPeriodika	2
http://linked.open...vai/riv/dodaniDat	2015
http://linked.open...aciTvurceVysledku	Dušek, Ladislav
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Lékařská fakulta
http://linked.open...dnocenehoVysledku	36057
http://linked.open...ai/riv/idVysledku	RIV/00216224:14110/14:00075682
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Isolated tumor cells; Low-volume disease; Lymph node dissection; Lymph node metastasis; Micrometastasis; Sentinel lymph node; Survival; Uterine cervical cancer (en)
http://linked.open.../riv/klicoveSlovo	Isolated tumor cells Low-volume disease Lymph node dissection Micrometastasis Uterine cervical cancer Survival Lymph node metastasis Sentinel lymph node
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[C18BDC35A1DC]
http://linked.open...i/riv/nazevZdroje	INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER
http://linked.open...in/vavai/riv/obor	FD
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	16 (xsd:int)
http://linked.open...UplatneniVysledku	2014
http://linked.open...v/svazekPeriodika	24
http://linked.open...iv/tvurceVysledku	Cibula, David Dušek, Ladislav Zikán, Michal Bats, Anne Sophie Dyduch, Grzegorz Graf, Petar Jach, Robert Kenter, Gemma G. Klat, Jaroslav Lécuru, Fabrice Mensdorff-Poully, Silvia von Querleu, Denid Sevcik, Libor Verheijen, René H.M. Zaal, Afra Zweemer, Ronald P.
http://linked.open...ain/vavai/riv/wos	000336489200020
issn	1048-891X
number of pages	9 (xsd:int)
http://bibframe.org/vocab/doi	10.1097/IGC.0000000000000043
http://localhost/t...ganizacniJednotka	14110

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