About: %22Stress entropic load%22 as a transgenerational epigenetic response trigger

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Epigenetic changes are generally based on the switching of alternative functional or structural states and result in the adaptation of cellular expression patterns during proliferation, differentiation or plastic changes in the adult organism, whereas some epigenetic information can be passed on other generations while other is not. Hence, the principal question is: why is some information reset or resolved during the meiosis process and other is passed from one generation to another, or, in other words: what %22adaptation trigger%22 level initiates transgenerationally transmitted epigenome change? Hereto, we propose a theory which states that stress, or, more specifically, the energy cost of an individual's adaptation to stress, represents a viable candidate for the transgenerational transmission trigger of a given acquired trait. Epigenetic changes are generally based on the switching of alternative functional or structural states and result in the adaptation of cellular expression patterns during proliferation, differentiation or plastic changes in the adult organism, whereas some epigenetic information can be passed on other generations while other is not. Hence, the principal question is: why is some information reset or resolved during the meiosis process and other is passed from one generation to another, or, in other words: what %22adaptation trigger%22 level initiates transgenerationally transmitted epigenome change? Hereto, we propose a theory which states that stress, or, more specifically, the energy cost of an individual's adaptation to stress, represents a viable candidate for the transgenerational transmission trigger of a given acquired trait. (en)
Title	%22Stress entropic load%22 as a transgenerational epigenetic response trigger %22Stress entropic load%22 as a transgenerational epigenetic response trigger (en)
skos:prefLabel	%22Stress entropic load%22 as a transgenerational epigenetic response trigger %22Stress entropic load%22 as a transgenerational epigenetic response trigger (en)
skos:notation	RIV/00216224:14110/14:00075489!RIV15-MSM-14110___
http://linked.open...avai/riv/aktivita	I P Z
http://linked.open...avai/riv/aktivity	I, P(ED2.1.00/03.0101), Z(MZ0MOU2005)
http://linked.open...iv/cisloPeriodika	3
http://linked.open...vai/riv/dodaniDat	2015
http://linked.open...aciTvurceVysledku	Nečesánek, Ivo Vinklárek, Jan Zlámal, Filip Novák, Jan Bienertová-Vašků, Julie
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Lékařská fakulta
http://linked.open...dnocenehoVysledku	47743
http://linked.open...ai/riv/idVysledku	RIV/00216224:14110/14:00075489
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	ALLOSTASIS; PLASTICITY (en)
http://linked.open.../riv/klicoveSlovo	PLASTICITY ALLOSTASIS
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[647E7B266855]
http://linked.open...i/riv/nazevZdroje	Medical Hypotheses
http://linked.open...in/vavai/riv/obor	ED
http://linked.open...ichTvurcuVysledku	5 (xsd:int)
http://linked.open...cetTvurcuVysledku	5 (xsd:int)
http://linked.open...vavai/riv/projekt	Regional Centre for Applied Molecular Oncology (RECAMO)
http://linked.open...UplatneniVysledku	2014
http://linked.open...v/svazekPeriodika	82
http://linked.open...iv/tvurceVysledku	Bienertová-Vašků, Julie Novák, Jan Zlámal, Filip Vinklárek, Jan Nečesánek, Ivo
http://linked.open...ain/vavai/riv/wos	000333494100006
http://linked.open...n/vavai/riv/zamer	Functional diagnostics of malignant tumours
issn	0306-9877
number of pages	4 (xsd:int)
http://bibframe.org/vocab/doi	10.1016/j.mehy.2013.12.008
http://localhost/t...ganizacniJednotka	14110

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