About: Bone Markers in the Treatment of Cancer Related Bone Disease in Patients with Metastatic Breast Cancer     Goto   Sponge   NotDistinct   Permalink

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  • Bone metastases and treatment-induced osteoporosis are frequently the maincauses of morbidity in patients with malignancies. Monitoring the level of bone markers (markers of bone metabolism) has been fairly well mapped in osteoporosis, where medical procedures can be modified according to the kinetics of marker levels before an answer can be evaluated by densitometry and before the onset of fractures. In bone metastases the role of these levels is not clear. The metabolic markers of bone resorption under review in this set were ß-Cross Laps (CTX) - a peptide that is a part of C - telopeptide, and N-terminal propeptide of collagen type 1 (P1NP). Material and methods: We monitored a group of 52 female patients with metastatic breastcancer. The patients received appropriate systemic treatment based on the immunohistochemistry of the tumor; the treatment consisted of hormone therapy or chemotherapy, and included parenteral bisphosphonates (ibandronate and zoledronic acid alternately).
  • Bone metastases and treatment-induced osteoporosis are frequently the maincauses of morbidity in patients with malignancies. Monitoring the level of bone markers (markers of bone metabolism) has been fairly well mapped in osteoporosis, where medical procedures can be modified according to the kinetics of marker levels before an answer can be evaluated by densitometry and before the onset of fractures. In bone metastases the role of these levels is not clear. The metabolic markers of bone resorption under review in this set were ß-Cross Laps (CTX) - a peptide that is a part of C - telopeptide, and N-terminal propeptide of collagen type 1 (P1NP). Material and methods: We monitored a group of 52 female patients with metastatic breastcancer. The patients received appropriate systemic treatment based on the immunohistochemistry of the tumor; the treatment consisted of hormone therapy or chemotherapy, and included parenteral bisphosphonates (ibandronate and zoledronic acid alternately). (en)
Title
  • Bone Markers in the Treatment of Cancer Related Bone Disease in Patients with Metastatic Breast Cancer
  • Bone Markers in the Treatment of Cancer Related Bone Disease in Patients with Metastatic Breast Cancer (en)
skos:prefLabel
  • Bone Markers in the Treatment of Cancer Related Bone Disease in Patients with Metastatic Breast Cancer
  • Bone Markers in the Treatment of Cancer Related Bone Disease in Patients with Metastatic Breast Cancer (en)
skos:notation
  • RIV/00216224:14110/14:00075299!RIV15-MSM-14110___
http://linked.open...avai/riv/aktivita
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  • 5680
http://linked.open...ai/riv/idVysledku
  • RIV/00216224:14110/14:00075299
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • metastatic breast cancer; bone markers-ß-Cross Laps (CTX); N-terminal propeptide of collagen type 1 (P1NP) (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [36527AAA6BFD]
http://linked.open...i/riv/nazevZdroje
  • Journal of Cancer Science and Therapy
http://linked.open...in/vavai/riv/obor
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http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 6
http://linked.open...iv/tvurceVysledku
  • Adam, Zdeněk
  • Mayer, Jiří
  • Bednařík, Otakar
  • Ostřížková, Lenka
  • Brančíková, Dagmar
  • Mechl, Zdeněk
  • Protivánková, Markéta
issn
  • 1948-5956
number of pages
http://bibframe.org/vocab/doi
  • 10.4172/1948-5956.1000244
http://localhost/t...ganizacniJednotka
  • 14110
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