About: Tissue profiling by nanogold-mediated mass spectrometry and artificial neural networks in the mouse model of human primary hyperoxaluria 1

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About: Tissue profiling by nanogold-mediated mass spectrometry and artificial neural networks in the mouse model of human primary hyperoxaluria 1 Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://www.sciencedirect.com/science/article/pii/S1214021X13000136/pdfft?md5=130a2f4ffcfb8294fae770ebd95924f2&pid=1-s2.0-S1214021X13000136-main.pdf
Description	Correct assessment of tissue histopathology is a necessary prerequisite for any clinical diagnosis. Nowadays, classical methods of histochemistry and immunohistochemistry are complemented by various techniques adopted from molecular biology and bioanalytical chemistry. Mass spectrometry profiling or imaging offered a new level of tissue visualization in the last decade, revealing hidden patterns of tissue molecular organization. It can be adapted to diagnostic purposes to improve decisions on complex and morphologically not apparent diagnoses. In this work, we successfully combined tissue profiling by mass spectrometry with analysis by artificial neural networks to classify normal and diseased liver and kidney tissues in a mouse model of primary hyperoxaluria type 1. Correct assessment of tissue histopathology is a necessary prerequisite for any clinical diagnosis. Nowadays, classical methods of histochemistry and immunohistochemistry are complemented by various techniques adopted from molecular biology and bioanalytical chemistry. Mass spectrometry profiling or imaging offered a new level of tissue visualization in the last decade, revealing hidden patterns of tissue molecular organization. It can be adapted to diagnostic purposes to improve decisions on complex and morphologically not apparent diagnoses. In this work, we successfully combined tissue profiling by mass spectrometry with analysis by artificial neural networks to classify normal and diseased liver and kidney tissues in a mouse model of primary hyperoxaluria type 1. (en)
Title	Tissue profiling by nanogold-mediated mass spectrometry and artificial neural networks in the mouse model of human primary hyperoxaluria 1 Tissue profiling by nanogold-mediated mass spectrometry and artificial neural networks in the mouse model of human primary hyperoxaluria 1 (en)
skos:prefLabel	Tissue profiling by nanogold-mediated mass spectrometry and artificial neural networks in the mouse model of human primary hyperoxaluria 1 Tissue profiling by nanogold-mediated mass spectrometry and artificial neural networks in the mouse model of human primary hyperoxaluria 1 (en)
skos:notation	RIV/00216224:14110/14:00073478!RIV15-MSM-14110___
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(ED1.100/02/0123), P(GA202/07/1669), Z(MSM0021622411), Z(MSM0021622430)
http://linked.open...iv/cisloPeriodika	2
http://linked.open...vai/riv/dodaniDat	2015
http://linked.open...aciTvurceVysledku	Houška, Jan Havel, Josef Hampl, Aleš Vaňhara, Petr
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Lékařská fakulta
http://linked.open...dnocenehoVysledku	50613
http://linked.open...ai/riv/idVysledku	RIV/00216224:14110/14:00073478
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	MALDI-TOF mass spectrometry; Primary hyperoxaluria I; Artificial neural networks; Diagnostics; Tissue profiling (en)
http://linked.open.../riv/klicoveSlovo	Tissue profiling Artificial neural networks MALDI-TOF mass spectrometry Diagnostics Primary hyperoxaluria I
http://linked.open...odStatuVydavatele	CZ - Česká republika
http://linked.open...ontrolniKodProRIV	[2397E97EAC9C]
http://linked.open...i/riv/nazevZdroje	Journal of Applied Biomedicine
http://linked.open...in/vavai/riv/obor	CB
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	7 (xsd:int)
http://linked.open...vavai/riv/projekt	Deposition of thermomehanically stable nanostructured diamond-like thin films in dual frequency capacitive discharges St. Anne´s University Hospital Brno - International Clinical Research Center (FNUSA-ICRC)
http://linked.open...UplatneniVysledku	2014
http://linked.open...v/svazekPeriodika	12
http://linked.open...iv/tvurceVysledku	Havel, Josef Hampl, Aleš Peña-Méndez, Eladia María Vaňhara, Petr Houška, Jan Hernandez-Fernaud, Juan Ramón Salido, Eduardo
http://linked.open...ain/vavai/riv/wos	000334441900007
http://linked.open...n/vavai/riv/zamer	Study and application of plasma chemical reactions in non-isothermic low temperature plasma and its interaction with solid surface Functional and molecular characteristics of cancer and normal stem cells - identification of targets for novel therapeutics and therapeutic strategies
issn	1214-021X
number of pages	7 (xsd:int)
http://bibframe.org/vocab/doi	10.1016/j.jab.2013.12.001
http://localhost/t...ganizacniJednotka	14110

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