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rdf:type
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Description
| - In this paper, we present a novel quantitative description of intracellular and t-tubular Ca2+ dynamics in a model of rat cardiac ventricular myocyte. In order to simulate recently published data, the model incorporates t-tubular and peripheral dyads and intracellular subspaces, segmentation of the t-tubular luminal volume, reformulation of the inactivation properties of t-tubular and peripheral L-type calcium current (ICa) and a description of exogenous Ca2+ buffer function in the intracellular space. The model is used to explore activity-induced changes of ion concentrations in the intracellular and t-tubular spaces and their role in excitation – contraction coupling in ventricular myocytes.
- In this paper, we present a novel quantitative description of intracellular and t-tubular Ca2+ dynamics in a model of rat cardiac ventricular myocyte. In order to simulate recently published data, the model incorporates t-tubular and peripheral dyads and intracellular subspaces, segmentation of the t-tubular luminal volume, reformulation of the inactivation properties of t-tubular and peripheral L-type calcium current (ICa) and a description of exogenous Ca2+ buffer function in the intracellular space. The model is used to explore activity-induced changes of ion concentrations in the intracellular and t-tubular spaces and their role in excitation – contraction coupling in ventricular myocytes. (en)
- In this paper, we present a novel quantitative description of intracellular and t-tubular Ca2+ dynamics in a model of rat cardiac ventricular myocyte. In order to simulate recently published data, the model incorporates t-tubular and peripheral dyads and intracellular subspaces, segmentation of the t-tubular luminal volume, reformulation of the inactivation properties of t-tubular and peripheral L-type calcium current (ICa) and a description of exogenous Ca2+ buffer function in the intracellular space. The model is used to explore activity-induced changes of ion concentrations in the intracellular and t-tubular spaces and their role in excitation – contraction coupling in ventricular myocytes. (cs)
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Title
| - A MATHEMATICAL MODEL OF RAT VENTRICULAR CARDIOMYOCYTE WITH A NOVEL DESCRIPTION OF INTRACELLULAR AND T-TUBULAR Ca2+ DYNAMICS
- A MATHEMATICAL MODEL OF RAT VENTRICULAR CARDIOMYOCYTE WITH A NOVEL DESCRIPTION OF INTRACELLULAR AND T-TUBULAR Ca2+ DYNAMICS (en)
- A MATHEMATICAL MODEL OF RAT VENTRICULAR CARDIOMYOCYTE WITH A NOVEL DESCRIPTION OF INTRACELLULAR AND T-TUBULAR Ca2+ DYNAMICS (cs)
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skos:prefLabel
| - A MATHEMATICAL MODEL OF RAT VENTRICULAR CARDIOMYOCYTE WITH A NOVEL DESCRIPTION OF INTRACELLULAR AND T-TUBULAR Ca2+ DYNAMICS
- A MATHEMATICAL MODEL OF RAT VENTRICULAR CARDIOMYOCYTE WITH A NOVEL DESCRIPTION OF INTRACELLULAR AND T-TUBULAR Ca2+ DYNAMICS (en)
- A MATHEMATICAL MODEL OF RAT VENTRICULAR CARDIOMYOCYTE WITH A NOVEL DESCRIPTION OF INTRACELLULAR AND T-TUBULAR Ca2+ DYNAMICS (cs)
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skos:notation
| - RIV/00216224:14110/13:00076820!RIV15-MSM-14110___
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/00216224:14110/13:00076820
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - cardiac cell; intracellular Ca2+ dynamics; t-tubule; quantitative modelling (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Pásek, Michal
- Šimurda, Jiří
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issn
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number of pages
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http://localhost/t...ganizacniJednotka
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