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  • Objectives – The aim of the study was to evaluate the long-term efficacy and hospitalization rates in children with refractory focal epilepsy treated by vagus nerve stimulation. Materials and methods – We retrospectively analyzed 15 children with intractable focal epilepsy treated by vagus nerve stimulation (mean age of 14.6 +/- 2.5 years at the time of implantation). We analyzed the treatment effectiveness at 1, 2, and 5 year follow-up visits. We counted the average number of urgent hospitalizations and number of days of urgent hospitalization per year for each patient before and after the VNS implantation. Results – The mean seizure reduction was 42.5% at 1 year, 54.9% at 2 years, and 58.3% at 5 years. The number of responders was 7 (46.7%) at 1 year and 9 (60%) at both 2 and 5 years. The mean number of urgent hospitalizations per patient was 1.0 +/- 0.6 per year preoperatively and 0.3 +/- 0.5 per year post-operatively. The mean number of days of urgent hospitalization per patient was 9.3 +/- 6.
  • Objectives – The aim of the study was to evaluate the long-term efficacy and hospitalization rates in children with refractory focal epilepsy treated by vagus nerve stimulation. Materials and methods – We retrospectively analyzed 15 children with intractable focal epilepsy treated by vagus nerve stimulation (mean age of 14.6 +/- 2.5 years at the time of implantation). We analyzed the treatment effectiveness at 1, 2, and 5 year follow-up visits. We counted the average number of urgent hospitalizations and number of days of urgent hospitalization per year for each patient before and after the VNS implantation. Results – The mean seizure reduction was 42.5% at 1 year, 54.9% at 2 years, and 58.3% at 5 years. The number of responders was 7 (46.7%) at 1 year and 9 (60%) at both 2 and 5 years. The mean number of urgent hospitalizations per patient was 1.0 +/- 0.6 per year preoperatively and 0.3 +/- 0.5 per year post-operatively. The mean number of days of urgent hospitalization per patient was 9.3 +/- 6. (en)
Title
  • Long-term vagus nerve stimulation in children with focal epilepsy
  • Long-term vagus nerve stimulation in children with focal epilepsy (en)
skos:prefLabel
  • Long-term vagus nerve stimulation in children with focal epilepsy
  • Long-term vagus nerve stimulation in children with focal epilepsy (en)
skos:notation
  • RIV/00216224:14110/13:00067788!RIV14-MSM-14110___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • I
http://linked.open...iv/cisloPeriodika
  • 5
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 85420
http://linked.open...ai/riv/idVysledku
  • RIV/00216224:14110/13:00067788
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • child neurology; epilepsy; quality of life; seizures; treatment (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [026F4929A584]
http://linked.open...i/riv/nazevZdroje
  • ACTA NEUROLOGICA SCANDINAVICA
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 127
http://linked.open...iv/tvurceVysledku
  • Kuba, Robert
  • Rektor, Ivan
  • Brázdil, Milan
  • Ryzí, Michal
  • Chrastina, Jan
  • Novák, Zdeněk
  • Ošlejšková, Hana
http://linked.open...ain/vavai/riv/wos
  • 000317859900006
issn
  • 0001-6314
number of pages
http://bibframe.org/vocab/doi
  • 10.1111/ane.12009
http://localhost/t...ganizacniJednotka
  • 14110
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