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  • Vitamin D as one of liposoluble vitamins has in clinical practice so far been related to children age and skeletal development. During the last years however, there has been a great deal of new information considering a rather more complicated involvement of vitamin D in a variety of processes and functions of the human body. So there is necessary to consider vitamin D not only as a vitamin but as a potent pleiotropic hormone. Vitamin D receptors were indentified in almost all tissues of human body. We can follow a growing body of information about the relationship between vitamin D and individual organ systems and their disorders currently. The long-term lack of vitamin D significantly potentiates cognitive deterioration in the elderly, influences the mood up to depression appearance. The positive relationship between vitamin D and the immune system functioning manifests in decreasing number of infective complications. Protective effect in carcinogenesis appears to be of high importance too.
  • Vitamin D as one of liposoluble vitamins has in clinical practice so far been related to children age and skeletal development. During the last years however, there has been a great deal of new information considering a rather more complicated involvement of vitamin D in a variety of processes and functions of the human body. So there is necessary to consider vitamin D not only as a vitamin but as a potent pleiotropic hormone. Vitamin D receptors were indentified in almost all tissues of human body. We can follow a growing body of information about the relationship between vitamin D and individual organ systems and their disorders currently. The long-term lack of vitamin D significantly potentiates cognitive deterioration in the elderly, influences the mood up to depression appearance. The positive relationship between vitamin D and the immune system functioning manifests in decreasing number of infective complications. Protective effect in carcinogenesis appears to be of high importance too. (en)
Title
  • Vitamin D as a pleiotropic hormone
  • Vitamin D as a pleiotropic hormone (en)
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  • Vitamin D as a pleiotropic hormone
  • Vitamin D as a pleiotropic hormone (en)
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  • RIV/00216224:14110/12:00062694!RIV13-MSM-14110___
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  • RIV/00216224:14110/12:00062694
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  • vitamin D - vitamin D receptor - sarcopenia - cardiac failure - dementia - depression (en)
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  • Matějovská Kubešová, Hana
  • Bielaková, Katarína
  • Topinkova, Eva
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  • 14110
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