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  • The aim of study was to examine relationship among levels of cytokines (IL-6, IL-13, IL-15, TNF-alpha) and chemokine (IL-8), production of autoantibodies, radiographic progression, and factors describing rheumatoid arthritis (RA). A total of 156 RA patients according to ACR criteria, and 55 control subjects were recruited into study. We observed higher levels of IL-15 within RA patients compared to healthy controls. Correlations among cytokine levels and the measures of rheumatoid factors, anti-CCP, measures of disease activity, and radiographic progression were observed. We conclude that IL-15 level in circulation could serve as one of the biomarkers for RA detection.
  • The aim of study was to examine relationship among levels of cytokines (IL-6, IL-13, IL-15, TNF-alpha) and chemokine (IL-8), production of autoantibodies, radiographic progression, and factors describing rheumatoid arthritis (RA). A total of 156 RA patients according to ACR criteria, and 55 control subjects were recruited into study. We observed higher levels of IL-15 within RA patients compared to healthy controls. Correlations among cytokine levels and the measures of rheumatoid factors, anti-CCP, measures of disease activity, and radiographic progression were observed. We conclude that IL-15 level in circulation could serve as one of the biomarkers for RA detection. (en)
Title
  • Circulating cytokine pattern and factors describing rheumatoid arthritis: IL-15 as one of the biomarkers for RA?
  • Circulating cytokine pattern and factors describing rheumatoid arthritis: IL-15 as one of the biomarkers for RA? (en)
skos:prefLabel
  • Circulating cytokine pattern and factors describing rheumatoid arthritis: IL-15 as one of the biomarkers for RA?
  • Circulating cytokine pattern and factors describing rheumatoid arthritis: IL-15 as one of the biomarkers for RA? (en)
skos:notation
  • RIV/00216224:14110/12:00061363!RIV13-MSM-14110___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • I
http://linked.open...iv/cisloPeriodika
  • 7
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 127249
http://linked.open...ai/riv/idVysledku
  • RIV/00216224:14110/12:00061363
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • rheumatoid arthritis; cytokine; interleukin; circulating level (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [68240A971AA6]
http://linked.open...i/riv/nazevZdroje
  • Biomarkers
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 17
http://linked.open...iv/tvurceVysledku
  • Jarkovský, Jiří
  • Němec, Petr
  • Souček, Miroslav
  • Vašků, Anna
  • Lipková, Jolana
  • Pávková Goldbergová, Monika
  • Gatterova, Jindra
  • Pávek, Nikolas
  • Stouracova, Martina
http://linked.open...ain/vavai/riv/wos
  • 000310077200011
issn
  • 1354-750X
number of pages
http://bibframe.org/vocab/doi
  • 10.3109/1354750X.2012.719036
http://localhost/t...ganizacniJednotka
  • 14110
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