About: Spectral Peak Frequency in Low-Frequency Band in Cross Spectra of Blood Pressure and Heart Rate Fluctuations in Young Type 1 Diabetic Patients     Goto   Sponge   NotDistinct   Permalink

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  • In this study we tested whether joint evaluation of the frequency (fcs) at which maxima of power in the cross-spectra between the variability in systolic blood pressure and inter-beat intervals in the range of 0.06-0.12 Hz occur together with the quantification of baroreflex sensitivity (BRS) may improve early detection of autonomic dysfunction in type 1 diabetes mellitus (T1DM). We measured 14 T1DM patients (age 20.3-24.2 years, DM duration 10.4-14.2 years, without any signs of autonomic neuropathy) and 14 age-matched controls (Co). Finger arterial blood pressure was continuously recorded by Finapres for one hour. BRS and fcs were determined by the spectral method. Receiver-operating curves (ROC) were calculated for fcs, BRS, and a combination of both factors determined as F(z)=1/(1+exp(-z)), z=3.09–0.013*BRS– 0.027*fcs. T1DM had significantly lower fcs than Co (T1DM: 88.8plusminus 6.7 vs. Co: 93.7plusminus 3.8 mHz; p<0.05), and a tendency towards lower BRS compared to Co (T1DM: 10.3 plusminus 4.
  • In this study we tested whether joint evaluation of the frequency (fcs) at which maxima of power in the cross-spectra between the variability in systolic blood pressure and inter-beat intervals in the range of 0.06-0.12 Hz occur together with the quantification of baroreflex sensitivity (BRS) may improve early detection of autonomic dysfunction in type 1 diabetes mellitus (T1DM). We measured 14 T1DM patients (age 20.3-24.2 years, DM duration 10.4-14.2 years, without any signs of autonomic neuropathy) and 14 age-matched controls (Co). Finger arterial blood pressure was continuously recorded by Finapres for one hour. BRS and fcs were determined by the spectral method. Receiver-operating curves (ROC) were calculated for fcs, BRS, and a combination of both factors determined as F(z)=1/(1+exp(-z)), z=3.09–0.013*BRS– 0.027*fcs. T1DM had significantly lower fcs than Co (T1DM: 88.8plusminus 6.7 vs. Co: 93.7plusminus 3.8 mHz; p<0.05), and a tendency towards lower BRS compared to Co (T1DM: 10.3 plusminus 4. (en)
Title
  • Spectral Peak Frequency in Low-Frequency Band in Cross Spectra of Blood Pressure and Heart Rate Fluctuations in Young Type 1 Diabetic Patients
  • Spectral Peak Frequency in Low-Frequency Band in Cross Spectra of Blood Pressure and Heart Rate Fluctuations in Young Type 1 Diabetic Patients (en)
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  • Spectral Peak Frequency in Low-Frequency Band in Cross Spectra of Blood Pressure and Heart Rate Fluctuations in Young Type 1 Diabetic Patients
  • Spectral Peak Frequency in Low-Frequency Band in Cross Spectra of Blood Pressure and Heart Rate Fluctuations in Young Type 1 Diabetic Patients (en)
skos:notation
  • RIV/00216224:14110/12:00061311!RIV13-MSM-14110___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • Z(MSM0021622402)
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  • 4
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http://linked.open...aciTvurceVysledku
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  • 170359
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  • RIV/00216224:14110/12:00061311
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  • Type 1 diabetes mellitus; Baroreflex sensitivity; Cross-spectral analysis; Frequency of spectral peak; Receiver operating curve (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • CZ - Česká republika
http://linked.open...ontrolniKodProRIV
  • [A6DC1B11962D]
http://linked.open...i/riv/nazevZdroje
  • Physiological Research
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
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http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 61
http://linked.open...iv/tvurceVysledku
  • Honzíková, Nataša
  • Krtička, Antonín
  • Závodná, Eva
  • Javorka, K.
  • Javorka, M.
  • Tonhajzerová, I.
http://linked.open...ain/vavai/riv/wos
  • 000309194600002
http://linked.open...n/vavai/riv/zamer
issn
  • 0862-8408
number of pages
http://localhost/t...ganizacniJednotka
  • 14110
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