About: Complete genome sequence of Treponema pallidum strain DAL-1

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About: Complete genome sequence of Treponema pallidum strain DAL-1 Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://standardsingenomics.org/index.php/sigen/article/view/sigs.2615838/784
Description	Treponema pallidum strain DAL-1 is a human uncultivable pathogen causing the sexually transmitted disease syphilis. Strain DAL-1 was isolated from the amniotic fluid of a pregnant woman in the secondary stage of syphilis. Here we describe the 1,139,971 bp long genome of T. pallidum strain DAL-1 which was sequenced using two independent sequencing methods (454 pyrosequencing and Illumina). In rabbits, strain DAL-1 replicated better than the T. pallidum strain Nichols. The comparison of the complete DAL-1 genome sequence with the Nichols sequence revealed a list of genetic differences that are potentially responsible for the increased rabbit virulence of the DAL-1 strain. Treponema pallidum strain DAL-1 is a human uncultivable pathogen causing the sexually transmitted disease syphilis. Strain DAL-1 was isolated from the amniotic fluid of a pregnant woman in the secondary stage of syphilis. Here we describe the 1,139,971 bp long genome of T. pallidum strain DAL-1 which was sequenced using two independent sequencing methods (454 pyrosequencing and Illumina). In rabbits, strain DAL-1 replicated better than the T. pallidum strain Nichols. The comparison of the complete DAL-1 genome sequence with the Nichols sequence revealed a list of genetic differences that are potentially responsible for the increased rabbit virulence of the DAL-1 strain. (en)
Title	Complete genome sequence of Treponema pallidum strain DAL-1 Complete genome sequence of Treponema pallidum strain DAL-1 (en)
skos:prefLabel	Complete genome sequence of Treponema pallidum strain DAL-1 Complete genome sequence of Treponema pallidum strain DAL-1 (en)
skos:notation	RIV/00216224:14110/12:00057665!RIV13-GA0-14110___
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA310/07/0321), Z(MSM0021622415)
http://linked.open...iv/cisloPeriodika	1
http://linked.open...vai/riv/dodaniDat	2013
http://linked.open...aciTvurceVysledku	Čejková, Darina Šmajs, David Zobaníková, Marie Strouhal, Michal Matějková, Petra Mikolka, Pavol
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Lékařská fakulta
http://linked.open...dnocenehoVysledku	128157
http://linked.open...ai/riv/idVysledku	RIV/00216224:14110/12:00057665
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Spirochaetaceae; Treponema pallidum; syphilis (en)
http://linked.open.../riv/klicoveSlovo	Treponema pallidum Spirochaetaceae syphilis
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[CB427FF9D974]
http://linked.open...i/riv/nazevZdroje	Standards in Genomic Sciences
http://linked.open...in/vavai/riv/obor	EB
http://linked.open...ichTvurcuVysledku	6 (xsd:int)
http://linked.open...cetTvurcuVysledku	9 (xsd:int)
http://linked.open...vavai/riv/projekt	Genomics of Treponema: comparative genome sequencing of pathogenic treponemes and transcriptome analysis of T. pallidum ssp. pallidum
http://linked.open...UplatneniVysledku	2012
http://linked.open...v/svazekPeriodika	7
http://linked.open...iv/tvurceVysledku	Chen, Lei Pospíšilová, Petra Qin, Xiang Strouhal, Michal Weinstock, George M. Zobaníková, Marie Čejková, Darina Šmajs, David Mikolka, Pavol
http://linked.open...n/vavai/riv/zamer	Molecular basis of cell and tissue regulations
issn	1944-3277
number of pages	13 (xsd:int)
http://bibframe.org/vocab/doi	10.4056/sigs.2615838
http://localhost/t...ganizacniJednotka	14110

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