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  • We have read with interest the study by Santangelo et al.,1 reporting the role of vascular pathology in the neuropsychological profile of parkinsonian patients. The authors evaluated whether the brain's vascular lesion load is associated with neuropsychological variables. They compared the neuropsychological profile of patients affected by Parkinsonism and vascular lesions to that of patients with Parkinson's disease (PD) without vascular lesions. The conclusion was that “regardless of the presence of dopaminergic denervation, cerebrovascular lesions … have an important effect in determining early onset and severity of cognitive impairment in patients with parkinsonism”. We agree with the authors that a comorbid cerebrovascular disease (CVD) may have an important impact on impairment of cognitive functions in patients with PD. In this aspect, the PD patients are not fundamentally different from patients without Parkinsonism.
  • We have read with interest the study by Santangelo et al.,1 reporting the role of vascular pathology in the neuropsychological profile of parkinsonian patients. The authors evaluated whether the brain's vascular lesion load is associated with neuropsychological variables. They compared the neuropsychological profile of patients affected by Parkinsonism and vascular lesions to that of patients with Parkinson's disease (PD) without vascular lesions. The conclusion was that “regardless of the presence of dopaminergic denervation, cerebrovascular lesions … have an important effect in determining early onset and severity of cognitive impairment in patients with parkinsonism”. We agree with the authors that a comorbid cerebrovascular disease (CVD) may have an important impact on impairment of cognitive functions in patients with PD. In this aspect, the PD patients are not fundamentally different from patients without Parkinsonism. (en)
Title
  • Pathology of Vessels Supplying the Brain in Patients with Parkinson's Disease
  • Pathology of Vessels Supplying the Brain in Patients with Parkinson's Disease (en)
skos:prefLabel
  • Pathology of Vessels Supplying the Brain in Patients with Parkinson's Disease
  • Pathology of Vessels Supplying the Brain in Patients with Parkinson's Disease (en)
skos:notation
  • RIV/00216224:14110/11:00080228!RIV15-MSM-14110___
http://linked.open...avai/riv/aktivita
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  • 219711
http://linked.open...ai/riv/idVysledku
  • RIV/00216224:14110/11:00080228
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • Parkinson's Disease; Pathology of Vessels (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [E88F7EBBCCB4]
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  • Movement Disorders
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http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 26
http://linked.open...iv/tvurceVysledku
  • Rektorová, Irena
  • Rektor, Ivan
http://linked.open...ain/vavai/riv/wos
  • 000291863600036
issn
  • 0885-3185
number of pages
http://bibframe.org/vocab/doi
  • 10.1002/mds.23444
http://localhost/t...ganizacniJednotka
  • 14110
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