About: History of treatment and long-term outcome in children with acute lymphoblastic leukemia in the Czech Republic

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About: History of treatment and long-term outcome in children with acute lymphoblastic leukemia in the Czech Republic Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Treatment of childhood acute lymphoblastic leukemia (ALL) was unifi ed in the year 1986 in the Czech Republic using BFM protocols. Patients and methods: Children were treated in 10 and later on in 8 centers localized at the pediatric departments of the biggest hospitals. More than 1.000 children and adolescents up to the age of 18 years were treated between 1986 and 2002 on three consecutive studies ALL-BFM 83, ALL-BFM 90 and ALL-BFM 95. Results: Event-free survival and overall survival improved gradually from 58/62% on ALL-BFM 83 through 70.5/76.6% on ALL-BFM 90 until 72.1/80.2% on ALL-BFM 95. At the same time the incidence of toxic deaths was decreasing and the success in the achievement of complete remission was increasing. Treatment of childhood acute lymphoblastic leukemia (ALL) was unifi ed in the year 1986 in the Czech Republic using BFM protocols. Patients and methods: Children were treated in 10 and later on in 8 centers localized at the pediatric departments of the biggest hospitals. More than 1.000 children and adolescents up to the age of 18 years were treated between 1986 and 2002 on three consecutive studies ALL-BFM 83, ALL-BFM 90 and ALL-BFM 95. Results: Event-free survival and overall survival improved gradually from 58/62% on ALL-BFM 83 through 70.5/76.6% on ALL-BFM 90 until 72.1/80.2% on ALL-BFM 95. At the same time the incidence of toxic deaths was decreasing and the success in the achievement of complete remission was increasing. (en)
Title	History of treatment and long-term outcome in children with acute lymphoblastic leukemia in the Czech Republic History of treatment and long-term outcome in children with acute lymphoblastic leukemia in the Czech Republic (en)
skos:prefLabel	History of treatment and long-term outcome in children with acute lymphoblastic leukemia in the Czech Republic History of treatment and long-term outcome in children with acute lymphoblastic leukemia in the Czech Republic (en)
skos:notation	RIV/00216224:14110/11:00059282!RIV13-MSM-14110___
http://linked.open...avai/riv/aktivita	I V
http://linked.open...avai/riv/aktivity	I, V
http://linked.open...iv/cisloPeriodika	3
http://linked.open...vai/riv/dodaniDat	2013
http://linked.open...aciTvurceVysledku	Štěrba, Jaroslav Hrstková, Hana
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Lékařská fakulta
http://linked.open...dnocenehoVysledku	202256
http://linked.open...ai/riv/idVysledku	RIV/00216224:14110/11:00059282
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Acute lymphoblastic leukaemia; children; treatment; diagnostics (en)
http://linked.open.../riv/klicoveSlovo	children diagnostics treatment Acute lymphoblastic leukaemia
http://linked.open...odStatuVydavatele	AT - Rakouská republika
http://linked.open...ontrolniKodProRIV	[4F9AA4255B71]
http://linked.open...i/riv/nazevZdroje	memo - Magazine of European Medical Oncology
http://linked.open...in/vavai/riv/obor	FA
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	27 (xsd:int)
http://linked.open...UplatneniVysledku	2011
http://linked.open...v/svazekPeriodika	4
http://linked.open...iv/tvurceVysledku	Hrstková, Hana Jarošová, M. Sedláček, P. Štěrba, Jaroslav Pospíšilová, D. Blažek, B. Gajdoš, P. Hak, J. Hrodek, O. Hrušák, O. Jabali, Y. Janotová, I. Mejstříková, E. Mihál, V. Procházková, D. Ptoszková, H. Smíšek, P. Starý, J. Timr, P. Toušovská, K. Trka, J. Vávra, V. Zdráhalová, K. Zemanová, Z. Zuna, J. Černá, Z. Šrámková, L.
issn	1865-5041
number of pages	6 (xsd:int)
http://bibframe.org/vocab/doi	10.1007/s12254-011-0289-9
http://localhost/t...ganizacniJednotka	14110

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