About: Main results of the Ouabain and Adducin for Specific Intervention on Sodium in Hypertension Trial (OASIS-HT): a randomized placebo-controlled phase-2 dose-finding study of rostafuroxin     Goto   Sponge   NotDistinct   Permalink

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  • The Ouabain and Adducin for Specific Intervention on Sodium in Hypertension (OASIS-HT) Trial was a phase-2 dose-finding study of rostafuroxin, a digitoxygenin derivative, which selectively antagonizes the effects of endogenous ouabain (EO) on Na+,K+-ATPase and mutated adducin. Rostafuroxin lowered blood pressure (BP) in some animal models and in humans.
  • The Ouabain and Adducin for Specific Intervention on Sodium in Hypertension (OASIS-HT) Trial was a phase-2 dose-finding study of rostafuroxin, a digitoxygenin derivative, which selectively antagonizes the effects of endogenous ouabain (EO) on Na+,K+-ATPase and mutated adducin. Rostafuroxin lowered blood pressure (BP) in some animal models and in humans. (en)
Title
  • Main results of the Ouabain and Adducin for Specific Intervention on Sodium in Hypertension Trial (OASIS-HT): a randomized placebo-controlled phase-2 dose-finding study of rostafuroxin
  • Main results of the Ouabain and Adducin for Specific Intervention on Sodium in Hypertension Trial (OASIS-HT): a randomized placebo-controlled phase-2 dose-finding study of rostafuroxin (en)
skos:prefLabel
  • Main results of the Ouabain and Adducin for Specific Intervention on Sodium in Hypertension Trial (OASIS-HT): a randomized placebo-controlled phase-2 dose-finding study of rostafuroxin
  • Main results of the Ouabain and Adducin for Specific Intervention on Sodium in Hypertension Trial (OASIS-HT): a randomized placebo-controlled phase-2 dose-finding study of rostafuroxin (en)
skos:notation
  • RIV/00216224:14110/11:00055577!RIV12-MSM-14110___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • I
http://linked.open...iv/cisloPeriodika
  • 13
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 210285
http://linked.open...ai/riv/idVysledku
  • RIV/00216224:14110/11:00055577
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • Hypertension; sodium; cardiovascular disease (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV
  • [79583A7F44C4]
http://linked.open...i/riv/nazevZdroje
  • Trials
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 12
http://linked.open...iv/tvurceVysledku
  • Souček, Miroslav
  • Nikitin, Yuri
  • Stolarz-Skrzypek, Katarzyna
  • Thijs, Lutgarde
  • Kawecka-Jaszcz, K.
  • Bacchieri, A.
  • Bartoň, John
  • Bianchi, G.
  • Citterio, Lorena
  • Dłużniewski, Miroslaw
  • Espositi, Ezio
  • Ferrari, P.
  • Glorioso, Nicola
  • Januszewicz, Andrzej
  • Lanzani, Chiara
  • Leeuw, Peter
  • Manunta, Paolo
  • Milyagin, Viktor
  • Staessen, Jan
  • Timio, Mario
  • Tykarski, Andrzej
  • Valentini, G.
http://linked.open...ain/vavai/riv/wos
  • 000286896900001
issn
  • 1745-6215
number of pages
http://bibframe.org/vocab/doi
  • 10.1186/1745-6215-12-13
http://localhost/t...ganizacniJednotka
  • 14110
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