About: Haematopoietic stem cell mobilization with plerixafor and G-CSF in patients with multiple myeloma transplanted with autologous stem cells     Goto   Sponge   NotDistinct   Permalink

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  • A proportion of patients with multiple myeloma (MM) who have already undergone autologous stem cell transplantation (autoSCT) might benefit from a further transplantation. For this, they might need to undergo another round of stem cell mobilization. We analyzed retrospectively the outcomes of stem cell mobilization with plerixafor and granulocyte colony-stimulating factor (G-CSF) in a group of 30 patients who had undergone autoSCT previously, and in 46 other patients. The previously transplanted patients were significantly different from the remaining patients with respect to the intensity and number of previous therapies. We observed that the median peripheral blood concentration of CD34+ cells after the first administration of plerixafor was lower in previously transplanted (19 cells/mu L) than in other patients (30 cells/mu L).
  • A proportion of patients with multiple myeloma (MM) who have already undergone autologous stem cell transplantation (autoSCT) might benefit from a further transplantation. For this, they might need to undergo another round of stem cell mobilization. We analyzed retrospectively the outcomes of stem cell mobilization with plerixafor and granulocyte colony-stimulating factor (G-CSF) in a group of 30 patients who had undergone autoSCT previously, and in 46 other patients. The previously transplanted patients were significantly different from the remaining patients with respect to the intensity and number of previous therapies. We observed that the median peripheral blood concentration of CD34+ cells after the first administration of plerixafor was lower in previously transplanted (19 cells/mu L) than in other patients (30 cells/mu L). (en)
Title
  • Haematopoietic stem cell mobilization with plerixafor and G-CSF in patients with multiple myeloma transplanted with autologous stem cells
  • Haematopoietic stem cell mobilization with plerixafor and G-CSF in patients with multiple myeloma transplanted with autologous stem cells (en)
skos:prefLabel
  • Haematopoietic stem cell mobilization with plerixafor and G-CSF in patients with multiple myeloma transplanted with autologous stem cells
  • Haematopoietic stem cell mobilization with plerixafor and G-CSF in patients with multiple myeloma transplanted with autologous stem cells (en)
skos:notation
  • RIV/00216224:14110/11:00055087!RIV12-MSM-14110___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • I
http://linked.open...iv/cisloPeriodika
  • 6
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
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http://linked.open...dnocenehoVysledku
  • 201648
http://linked.open...ai/riv/idVysledku
  • RIV/00216224:14110/11:00055087
http://linked.open...riv/jazykVysledku
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  • plerixafor; stem cell mobilization; myeloma; autologous stem cell transplantation (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [C3577A70458B]
http://linked.open...i/riv/nazevZdroje
  • European Journal of Haematology
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
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http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 86
http://linked.open...iv/tvurceVysledku
  • Mayer, Jiří
  • Kořístek, Zdeněk
  • Basak, Grzegorz W.
  • Basic-Kinda, Sandra
  • Giebel, Sebastian
  • Jaksic, Ozren
  • Labar, Boris
  • Masszi, Tamas
  • Mikala, Gabor
  • Wiktor-Jedrzejczak, Wieslaw
http://linked.open...ain/vavai/riv/wos
  • 000290731000005
issn
  • 0902-4441
number of pages
http://bibframe.org/vocab/doi
  • 10.1111/j.1600-0609.2011.01605.x
http://localhost/t...ganizacniJednotka
  • 14110
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