About: Flow Cytometric Phenotyping and Analysis of T Regulatory Cells in Multiple Myeloma Patients

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About: Flow Cytometric Phenotyping and Analysis of T Regulatory Cells in Multiple Myeloma Patients Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Multiple myeloma (MM) is a plasma cell (PC) disorder and associated with immune impairments. Flow cytometry based phenotyping and quantification of regulatory T cells (Tregs) enable to monitor the immune status of myeloma patients. Apart from enumeration of Tregs, functional characterization using proliferation or suppression assay adds key value in demonstrating the functional value of Tregs. Our study revealed that in MM patients Tregs are elevated compared to healthy subjects, which demonstrate the immune deregulation in MM. Multiple myeloma (MM) is a plasma cell (PC) disorder and associated with immune impairments. Flow cytometry based phenotyping and quantification of regulatory T cells (Tregs) enable to monitor the immune status of myeloma patients. Apart from enumeration of Tregs, functional characterization using proliferation or suppression assay adds key value in demonstrating the functional value of Tregs. Our study revealed that in MM patients Tregs are elevated compared to healthy subjects, which demonstrate the immune deregulation in MM. (en)
Title	Flow Cytometric Phenotyping and Analysis of T Regulatory Cells in Multiple Myeloma Patients Flow Cytometric Phenotyping and Analysis of T Regulatory Cells in Multiple Myeloma Patients (en)
skos:prefLabel	Flow Cytometric Phenotyping and Analysis of T Regulatory Cells in Multiple Myeloma Patients Flow Cytometric Phenotyping and Analysis of T Regulatory Cells in Multiple Myeloma Patients (en)
skos:notation	RIV/00216224:14110/11:00049839!RIV12-MZ0-14110___
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GAP304/10/1395), P(LC06027), P(NS10406), P(NS10408), Z(MSM0021622434)
http://linked.open...iv/cisloPeriodika	Suppl.
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Říhová, Lucie Hájek, Roman Muthu Raja, Karthick Raja Bartoňová, Jana
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Lékařská fakulta
http://linked.open...dnocenehoVysledku	199980
http://linked.open...ai/riv/idVysledku	RIV/00216224:14110/11:00049839
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Tregs; flow cytometry; multiple myeloma; thalidomide (en)
http://linked.open.../riv/klicoveSlovo	Tregs thalidomide flow cytometry multiple myeloma
http://linked.open...odStatuVydavatele	CZ - Česká republika
http://linked.open...ontrolniKodProRIV	[EDDAABE926EF]
http://linked.open...i/riv/nazevZdroje	Klinická onkologie
http://linked.open...in/vavai/riv/obor	FD
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...vavai/riv/projekt	Analysis of Clonal Plasma Cells Progenitors in Monoclonal Gammopathies University Research Centre - Czech Myeloma Group Creating of prognostic panel in patients with monoclonal gammopathy of undetermined significance with a target to prevent the risk of malignant transformation. Phenotype feature of B cells and plasma cells and its association with malignant transformation in monoclonal gammopathies
http://linked.open...UplatneniVysledku	2011
http://linked.open...v/svazekPeriodika	24
http://linked.open...iv/tvurceVysledku	Bartoňová, Jana Hájek, Roman Říhová, Lucie Muthu Raja, Karthick Raja
http://linked.open...n/vavai/riv/zamer	From classic prognostic markers to clinical applications in selected pharmacogenomic and pharmacoproteomic projects in multiple myeloma and monoclonal gammapathies
issn	0862-495X
number of pages	4 (xsd:int)
http://localhost/t...ganizacniJednotka	14110

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