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rdf:type
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Description
| - Background: Cytomegalovirus (CMV) infection is a life-threatening complication after solid organ transplantation. It usually appears in the first months after transplantation as a consequence of immunosuppression. The goal of this study was to evaluate the clinical significance of CD38high/CD3+8+ percentages in the detection of CMV infection in patients after kidney transplantation. Methods: In this retrospective study, 269 patients were monitored 2-3 months after renal transplantation for the percentage of CD38high/CD3+8+ lymphocytes estimated by flow-cytometry and for the number of CMV DNA copies in peripheral blood using a real-time polymerase chain reaction. Results: CMV infection was diagnosed in 12 (4.5%) patients between the 31st and 63rd days after transplantation, and all of them had percentages of CD38high/CD3+8+ T lymphocytes above 20%. In 4 of them, CMV DNAemia in peripheral blood was not detected, and 2 of these suffered from tissue-invasive CMV disease.
- Background: Cytomegalovirus (CMV) infection is a life-threatening complication after solid organ transplantation. It usually appears in the first months after transplantation as a consequence of immunosuppression. The goal of this study was to evaluate the clinical significance of CD38high/CD3+8+ percentages in the detection of CMV infection in patients after kidney transplantation. Methods: In this retrospective study, 269 patients were monitored 2-3 months after renal transplantation for the percentage of CD38high/CD3+8+ lymphocytes estimated by flow-cytometry and for the number of CMV DNA copies in peripheral blood using a real-time polymerase chain reaction. Results: CMV infection was diagnosed in 12 (4.5%) patients between the 31st and 63rd days after transplantation, and all of them had percentages of CD38high/CD3+8+ T lymphocytes above 20%. In 4 of them, CMV DNAemia in peripheral blood was not detected, and 2 of these suffered from tissue-invasive CMV disease. (en)
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Title
| - Monitoring of CD38high expression in peripheral blood CD8+ lymphocytes in patients after kidney transplantation as a marker of cytomegalovirus infection
- Monitoring of CD38high expression in peripheral blood CD8+ lymphocytes in patients after kidney transplantation as a marker of cytomegalovirus infection (en)
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skos:prefLabel
| - Monitoring of CD38high expression in peripheral blood CD8+ lymphocytes in patients after kidney transplantation as a marker of cytomegalovirus infection
- Monitoring of CD38high expression in peripheral blood CD8+ lymphocytes in patients after kidney transplantation as a marker of cytomegalovirus infection (en)
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skos:notation
| - RIV/00216224:14110/10:00056960!RIV12-MZ0-14110___
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/00216224:14110/10:00056960
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - CD38; Cytomegalovirus; Kidney transplant (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...vavai/riv/projekt
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Freiberger, Tomáš
- Litzman, Jiří
- Kuman, Milan
- Tichá, Olga
- Studeník, Pavel
- Štouračová, Martina
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http://linked.open...ain/vavai/riv/wos
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issn
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number of pages
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http://bibframe.org/vocab/doi
| - 10.1016/j.trim.2010.10.002
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http://localhost/t...ganizacniJednotka
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