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  • Type I diabetes (T1D) is an autoimmune, inflammatory disease, incurable up to date. This book reviews and discusses the progress on environmental triggers and endogenous alarmins linking innate immunity to the pathogenesis of type 1 diabetes. The potential anti-inflammatory treatments for T1D evaluated in several models of the disease are also examined. In addition, while many individual therapies provide partial protection against the development of autoimmune diabetes, recently developed multicomponent vaccine strategies hold promise for restoration of euglycemia and more durable maintenance of immunological homeostasis. This book discusses mechanisms underlying the onset and development of type I diabetes and assesses individual and multicomponent immunosuppression strategies. The T1D associated genes that have been replicated in different populations are also analyzed, and whether they could lead to the genetic diagnosis.
  • Type I diabetes (T1D) is an autoimmune, inflammatory disease, incurable up to date. This book reviews and discusses the progress on environmental triggers and endogenous alarmins linking innate immunity to the pathogenesis of type 1 diabetes. The potential anti-inflammatory treatments for T1D evaluated in several models of the disease are also examined. In addition, while many individual therapies provide partial protection against the development of autoimmune diabetes, recently developed multicomponent vaccine strategies hold promise for restoration of euglycemia and more durable maintenance of immunological homeostasis. This book discusses mechanisms underlying the onset and development of type I diabetes and assesses individual and multicomponent immunosuppression strategies. The T1D associated genes that have been replicated in different populations are also analyzed, and whether they could lead to the genetic diagnosis. (en)
Title
  • Nonconventional Variability Analysis of Cardiovascular Signals in Diabetes Mellitus
  • Nonconventional Variability Analysis of Cardiovascular Signals in Diabetes Mellitus (en)
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  • Nonconventional Variability Analysis of Cardiovascular Signals in Diabetes Mellitus
  • Nonconventional Variability Analysis of Cardiovascular Signals in Diabetes Mellitus (en)
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  • RIV/00216224:14110/10:00056414!RIV12-MSM-14110___
http://linked.open...avai/riv/aktivita
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  • I
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  • 274987
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  • RIV/00216224:14110/10:00056414
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  • type I Diabetes mellitus; children; genetics; baroreflex sensitivity (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...ontrolniKodProRIV
  • [AD919C104DD4]
http://linked.open...i/riv/mistoVydani
  • New York
http://linked.open...vEdiceCisloSvazku
  • Metabolic Diseases
http://linked.open...i/riv/nazevZdroje
  • Handbook of Type 1 Diabetes Mellitus: Etiology, Diagnosis, and Treatment
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...v/pocetStranKnihy
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http://linked.open...UplatneniVysledku
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  • Baumert, Mathias
  • Honzíková, Nataša
  • Javorka, Kamil
  • Javorka, Michal
  • Lazarova, Zuzana
  • Tonhajzerova, Ingrid
  • Turianikova, Zuzana
number of pages
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  • Nova Science Publishers
https://schema.org/isbn
  • 978-1-60741-311-0
http://localhost/t...ganizacniJednotka
  • 14110
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