About: Association of FcRn expression with lung abnormalities and IVIG catabolism in patients with common variable immunodeficiency     Goto   Sponge   NotDistinct   Permalink

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Description
  • Patients with generalized bronchiectasis and fibrosis had lower levels of FCRN mRNA compared to patients without these complications. Moreover, FCRN mRNA levels correlated negatively with the extent of bronchiectasis and the rate of IgG decline after infusion of IVIG.Our results showed that FcRn might play a role in the development of lung structural abnormalities and in the catabolism of IVIG in patients with CVID.
  • Patients with generalized bronchiectasis and fibrosis had lower levels of FCRN mRNA compared to patients without these complications. Moreover, FCRN mRNA levels correlated negatively with the extent of bronchiectasis and the rate of IgG decline after infusion of IVIG.Our results showed that FcRn might play a role in the development of lung structural abnormalities and in the catabolism of IVIG in patients with CVID. (en)
Title
  • Association of FcRn expression with lung abnormalities and IVIG catabolism in patients with common variable immunodeficiency
  • Association of FcRn expression with lung abnormalities and IVIG catabolism in patients with common variable immunodeficiency (en)
skos:prefLabel
  • Association of FcRn expression with lung abnormalities and IVIG catabolism in patients with common variable immunodeficiency
  • Association of FcRn expression with lung abnormalities and IVIG catabolism in patients with common variable immunodeficiency (en)
skos:notation
  • RIV/00216224:14110/10:00051454!RIV12-MSM-14110___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(NR9192), V
http://linked.open...iv/cisloPeriodika
  • 3
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
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http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 247959
http://linked.open...ai/riv/idVysledku
  • RIV/00216224:14110/10:00051454
http://linked.open...riv/jazykVysledku
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  • Neonatal Fc receptor; FcRn; Common variable immunodeficiency; Lung disease; IVIG (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [6CE3B8A42F50]
http://linked.open...i/riv/nazevZdroje
  • CLINICAL IMMUNOLOGY
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http://linked.open...v/svazekPeriodika
  • 136
http://linked.open...iv/tvurceVysledku
  • Freiberger, Tomáš
  • Jarkovský, Jiří
  • Litzman, Jiří
  • Ravčuková, Barbora
  • Thon, Vojtěch
  • Vlček, Jiří
  • Grodecká, Lucie
  • Postránecká, Věra
  • Kuřecová, Barbora
http://linked.open...ain/vavai/riv/wos
  • 000280907000011
issn
  • 1521-6616
number of pages
http://bibframe.org/vocab/doi
  • 10.1016/j.clim.2010.05.006
http://localhost/t...ganizacniJednotka
  • 14110
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