About: No association of FCRN promoter VNTR polymorphism with the rate of maternal-fetal IgG transfer

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About: No association of FCRN promoter VNTR polymorphism with the rate of maternal-fetal IgG transfer Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The neonatal Fc receptor (FcRn) plays a critical role in maternal-fetal IgG transfer. Recently, a functionally active promoter polymorphism in the FCRN gene, represented by variable number of tandem repeats (VNTR), has been described. We analysed 103 single fetal samples and 103 paired maternal and fetal samples collected from umbilical cord blood of full-term neonates born from the 38th to the 41st week of pregnancy and detected no significant influence of maternal FCRN VNTR genotype on maternal IgG levels or of fetal FCRN VNTR genotype on fetal IgG levels or the fetal/maternal IgG ratio. The neonatal Fc receptor (FcRn) plays a critical role in maternal-fetal IgG transfer. Recently, a functionally active promoter polymorphism in the FCRN gene, represented by variable number of tandem repeats (VNTR), has been described. We analysed 103 single fetal samples and 103 paired maternal and fetal samples collected from umbilical cord blood of full-term neonates born from the 38th to the 41st week of pregnancy and detected no significant influence of maternal FCRN VNTR genotype on maternal IgG levels or of fetal FCRN VNTR genotype on fetal IgG levels or the fetal/maternal IgG ratio. (en)
Title	No association of FCRN promoter VNTR polymorphism with the rate of maternal-fetal IgG transfer No association of FCRN promoter VNTR polymorphism with the rate of maternal-fetal IgG transfer (en)
skos:prefLabel	No association of FCRN promoter VNTR polymorphism with the rate of maternal-fetal IgG transfer No association of FCRN promoter VNTR polymorphism with the rate of maternal-fetal IgG transfer (en)
skos:notation	RIV/00216224:14110/10:00051452!RIV12-MSM-14110___
http://linked.open...avai/riv/aktivita	I P
http://linked.open...avai/riv/aktivity	I, P(NR9192)
http://linked.open...iv/cisloPeriodika	2
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Thon, Vojtěch Litzman, Jiří Bartoňková, Dana Freiberger, Tomáš Jarkovský, Jiří
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Lékařská fakulta
http://linked.open...dnocenehoVysledku	274928
http://linked.open...ai/riv/idVysledku	RIV/00216224:14110/10:00051452
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Neonatal Fc receptor; FcRn; VNTR; Polymorphism; Maternal-fetal IgG transfer (en)
http://linked.open.../riv/klicoveSlovo	FcRn Neonatal Fc receptor Polymorphism Maternal-fetal IgG transfer VNTR
http://linked.open...odStatuVydavatele	IE - Irsko
http://linked.open...ontrolniKodProRIV	[232126760AC3]
http://linked.open...i/riv/nazevZdroje	Journal of Reproductive Immunology
http://linked.open...in/vavai/riv/obor	EC
http://linked.open...ichTvurcuVysledku	5 (xsd:int)
http://linked.open...cetTvurcuVysledku	8 (xsd:int)
http://linked.open...vavai/riv/projekt	Screening of mutations and polymorphisms in neonatal Fc receptor gene in patients with primary disorders of antibody production
http://linked.open...UplatneniVysledku	2010
http://linked.open...v/svazekPeriodika	85
http://linked.open...iv/tvurceVysledku	Freiberger, Tomáš Jarkovský, Jiří Litzman, Jiří Ravčuková, Barbora Thon, Vojtěch Bartoňková, Dana Grodecká, Lucie Kuřecová, Barbora
http://linked.open...ain/vavai/riv/wos	000279888600010
issn	0165-0378
number of pages	5 (xsd:int)
http://bibframe.org/vocab/doi	10.1016/j.jri.2010.04.002
http://localhost/t...ganizacniJednotka	14110

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