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  • We performed a retrospective, multicenter, open-label study to evaluate the efficacy Of vagus nerve stimulation (VNS) in all patients in the Czech Republic who have received this treatment for at least 5 years (n = 90). The mean last follow-up was 6.6 +/- 1.1 years (79 +/- 13 months). The median number of seizures among all patients decreased from 41.2 seizures/month in the prestimulation period to 14.9 seizures/month at 5 years follow-up visit. The mean percentage of seizure reduction was 55.9%. The responder rate in these patients is in concordance with the decrease of overall seizure frequency. At 1 year after beginning the stimulation, 44.4% of patients were responders; this percentage increased to 58.7% after 2 years. At the 5 years last follow-up 64.4% of patients were responders, 15.5% experienced >= 90% seizure reduction, and 5.5% were seizure-free. A separate analysis of patients younger than 16 years of age showed lower efficacy rates of VNS in comparison to the whole group.
  • We performed a retrospective, multicenter, open-label study to evaluate the efficacy Of vagus nerve stimulation (VNS) in all patients in the Czech Republic who have received this treatment for at least 5 years (n = 90). The mean last follow-up was 6.6 +/- 1.1 years (79 +/- 13 months). The median number of seizures among all patients decreased from 41.2 seizures/month in the prestimulation period to 14.9 seizures/month at 5 years follow-up visit. The mean percentage of seizure reduction was 55.9%. The responder rate in these patients is in concordance with the decrease of overall seizure frequency. At 1 year after beginning the stimulation, 44.4% of patients were responders; this percentage increased to 58.7% after 2 years. At the 5 years last follow-up 64.4% of patients were responders, 15.5% experienced >= 90% seizure reduction, and 5.5% were seizure-free. A separate analysis of patients younger than 16 years of age showed lower efficacy rates of VNS in comparison to the whole group. (en)
Title
  • Vagus nerve stimulation: Longitudinal follow-up patients treated for 5 years.
  • Vagus nerve stimulation: Longitudinal follow-up patients treated for 5 years. (en)
skos:prefLabel
  • Vagus nerve stimulation: Longitudinal follow-up patients treated for 5 years.
  • Vagus nerve stimulation: Longitudinal follow-up patients treated for 5 years. (en)
skos:notation
  • RIV/00216224:14110/09:00051164!RIV12-MSM-14110___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • I, P(1D/2/16/II/04), S, V, Z(MSM0021622404)
http://linked.open...iv/cisloPeriodika
  • 4
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 348349
http://linked.open...ai/riv/idVysledku
  • RIV/00216224:14110/09:00051164
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • vagus nerve stimulation; efficacy; long-term outcome; comlications (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV
  • [00B4EC9A577D]
http://linked.open...i/riv/nazevZdroje
  • Seizure
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 18
http://linked.open...iv/tvurceVysledku
  • Komárek, Vladimír
  • Marusič, Petr
  • Kuba, Robert
  • Rektor, Ivan
  • Brázdil, Milan
  • Hadač, Jan
  • Hovorka, Jiří
  • Procházka, Tomáš
  • Sebroňová, Věra
  • Kalina, Miroslav
  • Zarubova, Jana
  • Ošlejšková, Hana
  • Nežádal, Tomáš
  • Brožová, Klára
http://linked.open...ain/vavai/riv/wos
  • 000265465000007
http://linked.open...n/vavai/riv/zamer
issn
  • 1059-1311
number of pages
http://bibframe.org/vocab/doi
  • 10.1016/j.seizure.2008.10.012
http://localhost/t...ganizacniJednotka
  • 14110
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