About: Regression of histopathological myopathic changes in patients with critical illness neuromuscular disorders

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About: Regression of histopathological myopathic changes in patients with critical illness neuromuscular disorders Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Histopathological analysis of 52 muscle biopsies from 43 adult critically ill patients was performed to determine the differential diagnosis and course of neuromuscular involvement in critically ill patients suffering from critical illness polyneuropathy or myopathy. The first histopathological examination in all 43 patients revealed signs of neuropathy in 2 biopsies, myopathy in 19 biopsies, and neuromyopathy in 18, including type 2 fibre atrophy. A repeat study of 9 patients showed that the histopathological features changed in all cases. A second biopsy performed several months or years after the first revealed that myopathic features had regressed and either recovery to normal histopathological findings had occurred or evidence of a persistent neurogenic lesion was found. The results indicate that muscle involvement in critically ill patients is reversible. Histopathological analysis of 52 muscle biopsies from 43 adult critically ill patients was performed to determine the differential diagnosis and course of neuromuscular involvement in critically ill patients suffering from critical illness polyneuropathy or myopathy. The first histopathological examination in all 43 patients revealed signs of neuropathy in 2 biopsies, myopathy in 19 biopsies, and neuromyopathy in 18, including type 2 fibre atrophy. A repeat study of 9 patients showed that the histopathological features changed in all cases. A second biopsy performed several months or years after the first revealed that myopathic features had regressed and either recovery to normal histopathological findings had occurred or evidence of a persistent neurogenic lesion was found. The results indicate that muscle involvement in critically ill patients is reversible. (en)
Title	Regression of histopathological myopathic changes in patients with critical illness neuromuscular disorders Regression of histopathological myopathic changes in patients with critical illness neuromuscular disorders (en)
skos:prefLabel	Regression of histopathological myopathic changes in patients with critical illness neuromuscular disorders Regression of histopathological myopathic changes in patients with critical illness neuromuscular disorders (en)
skos:notation	RIV/00216224:14110/09:00038026!RIV10-MSM-14110___
http://linked.open...avai/riv/aktivita	Z
http://linked.open...avai/riv/aktivity	Z(MSM0021620819), Z(MSM0021622404)
http://linked.open...iv/cisloPeriodika	3
http://linked.open...vai/riv/dodaniDat	2010
http://linked.open...aciTvurceVysledku	Bednařík, Josef Lukáš, Zdeněk
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Lékařská fakulta
http://linked.open...dnocenehoVysledku	338654
http://linked.open...ai/riv/idVysledku	RIV/00216224:14110/09:00038026
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	critical illness polyneuropathy; critical illness myopathy; diagnosis; biopsy; follow-up study (en)
http://linked.open.../riv/klicoveSlovo	diagnosis biopsy follow-up study critical illness myopathy critical illness polyneuropathy
http://linked.open...odStatuVydavatele	CZ - Česká republika
http://linked.open...ontrolniKodProRIV	[2237D657CF14]
http://linked.open...i/riv/nazevZdroje	Scripta Medica
http://linked.open...in/vavai/riv/obor	FH
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...UplatneniVysledku	2009
http://linked.open...v/svazekPeriodika	82
http://linked.open...iv/tvurceVysledku	Bednařík, Josef Lukáš, Zdeněk Maňák, Jan Schreiber, M.
http://linked.open...n/vavai/riv/zamer	Náhrada a podpora funkce některých životně důležitých orgánů The Internal Organisation and Neurobiological Mechanisms of Functional CNS Systems under Normal and Pathological Conditions
issn	1211-3395
number of pages	11 (xsd:int)
http://localhost/t...ganizacniJednotka	14110

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