About: Association between variants in the genes for leptin, leptin receptor, and proopiomelanocortin with chronic heart failure in the Czech population     Goto   Sponge   NotDistinct   Permalink

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Description
  • Patients with chronic heart failure (CHF) express enhanced catabolic metabolism finally resulting in overall weight loss, whereas adipokines might play a crucial role in signaling among tissues. The role of the polymorphic variants in the genes encoding for adipokines as potential CHF susceptibility genes is unclear. Based on our findings, the LEPR Gln223Arg polymorphism could be considered a disease susceptibility modulating factor both in ischemic heart disease or dilated cardiomyopathy patients.
  • Patients with chronic heart failure (CHF) express enhanced catabolic metabolism finally resulting in overall weight loss, whereas adipokines might play a crucial role in signaling among tissues. The role of the polymorphic variants in the genes encoding for adipokines as potential CHF susceptibility genes is unclear. Based on our findings, the LEPR Gln223Arg polymorphism could be considered a disease susceptibility modulating factor both in ischemic heart disease or dilated cardiomyopathy patients. (en)
Title
  • Association between variants in the genes for leptin, leptin receptor, and proopiomelanocortin with chronic heart failure in the Czech population
  • Association between variants in the genes for leptin, leptin receptor, and proopiomelanocortin with chronic heart failure in the Czech population (en)
skos:prefLabel
  • Association between variants in the genes for leptin, leptin receptor, and proopiomelanocortin with chronic heart failure in the Czech population
  • Association between variants in the genes for leptin, leptin receptor, and proopiomelanocortin with chronic heart failure in the Czech population (en)
skos:notation
  • RIV/00216224:14110/09:00033786!RIV10-MSM-14110___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • V
http://linked.open...iv/cisloPeriodika
  • 2
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 304241
http://linked.open...ai/riv/idVysledku
  • RIV/00216224:14110/09:00033786
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • Adipokines; Polymorphisms; Leptin; Leptin receptor; Proopiomelanocortin; Chronic heart failure (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • JP - Japonsko
http://linked.open...ontrolniKodProRIV
  • [B92C309ECE6E]
http://linked.open...i/riv/nazevZdroje
  • Heart Vessels
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 24/2009
http://linked.open...iv/tvurceVysledku
  • Bienertová Vašků, Julie
  • Bienert, Petr
  • Vašků, Anna
  • Špinarová, Lenka
http://linked.open...ain/vavai/riv/wos
  • 000264836000010
issn
  • 0910-8327
number of pages
http://localhost/t...ganizacniJednotka
  • 14110
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