About: The association of interleukin-6 (IL-6) haplotypes with plaque-induced gingivitis in children     Goto   Sponge   NotDistinct   Permalink

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Description
  • The proinflammatory cytokine interleukin-6 (IL-6) is a key regulator of the host response to microbial infection and major modulator of extracellular matrix catabolism and bone resorption. The aim of this case-control study was to test differences between children with and without gingivitis in distribution of IL-6 alleles at positions -174, -572, and -597 and their haplotypes. Our results indicate that the three promoter polymorphisms in the IL-6 gene act in a cooperative fashion and suggest that IL-6 haplotypes could play a role in the pathogenesis of gingivitis in Caucasian children.
  • The proinflammatory cytokine interleukin-6 (IL-6) is a key regulator of the host response to microbial infection and major modulator of extracellular matrix catabolism and bone resorption. The aim of this case-control study was to test differences between children with and without gingivitis in distribution of IL-6 alleles at positions -174, -572, and -597 and their haplotypes. Our results indicate that the three promoter polymorphisms in the IL-6 gene act in a cooperative fashion and suggest that IL-6 haplotypes could play a role in the pathogenesis of gingivitis in Caucasian children. (en)
Title
  • The association of interleukin-6 (IL-6) haplotypes with plaque-induced gingivitis in children
  • The association of interleukin-6 (IL-6) haplotypes with plaque-induced gingivitis in children (en)
skos:prefLabel
  • The association of interleukin-6 (IL-6) haplotypes with plaque-induced gingivitis in children
  • The association of interleukin-6 (IL-6) haplotypes with plaque-induced gingivitis in children (en)
skos:notation
  • RIV/00216224:14110/08:00025790!RIV10-MZ0-14110___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(1M0528), P(NR8394), P(NR9129)
http://linked.open...iv/cisloPeriodika
  • 2
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 357171
http://linked.open...ai/riv/idVysledku
  • RIV/00216224:14110/08:00025790
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • cytokine; gene; gingivitis; PCR; polymorphism (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • SE - Švédské království
http://linked.open...ontrolniKodProRIV
  • [C5E814BF993A]
http://linked.open...i/riv/nazevZdroje
  • Acta Odontologica Scandinavica
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 66
http://linked.open...iv/tvurceVysledku
  • Izakovičová-Hollá, Lydie
  • Kukla, Lubomír
  • Kukletová, Martina
  • Vokurka, Jan
  • Musilová, Kristína
  • Klapušová, Lucie
  • Pantučková, Pavla
  • Znojil, Vladimír
http://linked.open...ain/vavai/riv/wos
  • 000255441100007
issn
  • 0001-6357
number of pages
http://localhost/t...ganizacniJednotka
  • 14110
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