About: Single-cell c-myc gene expression in relationship to nuclear domains.

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Single-cell c-myc gene expression in relationship to nuclear domains. Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Nuclear locations of the c-myc gene and its transcripts (c-myc (T)) have been investigated in relation to nuclear domains involved in RNA synthesis and processing. Transcription of the c-myc gene appears to be linked to the late G(1)- and preferentially to S-phases of the cell cycle. The c-myc gene and its transcripts were positioned non-randomly within the interphase nucleus; additionally, c-myc RNA signals accumulated at nucleoli. Using oligo-probes, designed to exon II and exon III of the c-myc gene, single c-myc (T) was preferentially observed in human carcinoma HT29 and A549 cells. Conversely, human embryonal teratocarcinoma NTERA cells were characterized by the presence of multiple c-myc RNA signals located in both the nucleoli and nucleoplasm. When accumulated at nucleoli, c-myc (T) occupied the periphery of this organelle, though not those associated with the cultivation surface. Nuclear locations of the c-myc gene and its transcripts (c-myc (T)) have been investigated in relation to nuclear domains involved in RNA synthesis and processing. Transcription of the c-myc gene appears to be linked to the late G(1)- and preferentially to S-phases of the cell cycle. The c-myc gene and its transcripts were positioned non-randomly within the interphase nucleus; additionally, c-myc RNA signals accumulated at nucleoli. Using oligo-probes, designed to exon II and exon III of the c-myc gene, single c-myc (T) was preferentially observed in human carcinoma HT29 and A549 cells. Conversely, human embryonal teratocarcinoma NTERA cells were characterized by the presence of multiple c-myc RNA signals located in both the nucleoli and nucleoplasm. When accumulated at nucleoli, c-myc (T) occupied the periphery of this organelle, though not those associated with the cultivation surface. (en)
Title	Single-cell c-myc gene expression in relationship to nuclear domains. Single-cell c-myc gene expression in relationship to nuclear domains. (en)
skos:prefLabel	Single-cell c-myc gene expression in relationship to nuclear domains. Single-cell c-myc gene expression in relationship to nuclear domains. (en)
skos:notation	RIV/00216224:14110/08:00024465!RIV10-MSM-14110___
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(1P05OC084), P(1QS500040508), P(GA204/06/0978), P(IAA5004306), P(LC06027), P(LC535), Z(AV0Z50040507), Z(AV0Z50040702)
http://linked.open...iv/cisloPeriodika	2
http://linked.open...vai/riv/dodaniDat	2010
http://linked.open...aciTvurceVysledku	Strašák, Luděk Kozubek, Stanislav Harničarová Horáková, Andrea
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Lékařská fakulta
http://linked.open...dnocenehoVysledku	394974
http://linked.open...ai/riv/idVysledku	RIV/00216224:14110/08:00024465
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	c-myc gene; nuclear speckles; nucleolus; promyelocytic leukaemia body; transcription site (en)
http://linked.open.../riv/klicoveSlovo	nucleolus c-myc gene nuclear speckles promyelocytic leukaemia body transcription site
http://linked.open...odStatuVydavatele	CZ - Česká republika
http://linked.open...ontrolniKodProRIV	[BFD2C7C3E45D]
http://linked.open...i/riv/nazevZdroje	Chromosome Research
http://linked.open...in/vavai/riv/obor	EB
http://linked.open...ichTvurcuVysledku	3 (xsd:int)
http://linked.open...cetTvurcuVysledku	5 (xsd:int)
http://linked.open...vavai/riv/projekt	Dynamic structure and function of the cell nucleus after irradiation Methylation of histone H3 as a prognostic marker of chronic myeloid leukemia remission Chromosome dynamics and organization during the cell cycle in normal and pathologic conditions University Research Centre - Czech Myeloma Group Postranslational modifications of histones after cell treatment by inhibitors of histone deacetylases and during induction of cell differentiation Human genome structure
http://linked.open...UplatneniVysledku	2008
http://linked.open...v/svazekPeriodika	16
http://linked.open...iv/tvurceVysledku	Bártová, Eva Kozubek, Stanislav Krejčí, Jana Strašák, Luděk Harničarová, Andrea
http://linked.open...n/vavai/riv/zamer	Biophysics of dynamic structures and functions of biological systems Genome and epigenome: 1D and 3D Structure, Dynamics, Interactions with Proteins and Functions
issn	0967-3849
number of pages	19 (xsd:int)
http://localhost/t...ganizacniJednotka	14110

Faceted Search & Find service v1.16.118 as of Jun 21 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 58 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software