About: Prevention of bone bridge formation using transplantation of the autogenous mesenchymal stem cells to physeal defects: an experimental study in rabbits.

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About: Prevention of bone bridge formation using transplantation of the autogenous mesenchymal stem cells to physeal defects: an experimental study in rabbits. Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Preventive transplantation of autogenous mesenchymal stem cells into iatrogenically created defect in femoral distal growth plate in rabbit prevented origination of a bone bridge and healed the physeal defect in by hyaline cartilage. Immunofluorescence examination proved that the newly created chondrocytes originated in the growth zone as a result of differentiation of implanted MSCs. Growth of the right femur in the traumatized physis was preserved after transplantation of autogenous MSCs and, compared to the left femur (with physeal defect but without transplanted MSCs), substantial shortening and valgus deformity of the bone did not occur (p=0.018). Preventive transplantation of autogenous mesenchymal stem cells into iatrogenically created defect in femoral distal growth plate in rabbit prevented origination of a bone bridge and healed the physeal defect in by hyaline cartilage. Immunofluorescence examination proved that the newly created chondrocytes originated in the growth zone as a result of differentiation of implanted MSCs. Growth of the right femur in the traumatized physis was preserved after transplantation of autogenous MSCs and, compared to the left femur (with physeal defect but without transplanted MSCs), substantial shortening and valgus deformity of the bone did not occur (p=0.018). (en)
Title	Prevention of bone bridge formation using transplantation of the autogenous mesenchymal stem cells to physeal defects: an experimental study in rabbits. Prevention of bone bridge formation using transplantation of the autogenous mesenchymal stem cells to physeal defects: an experimental study in rabbits. (en)
skos:prefLabel	Prevention of bone bridge formation using transplantation of the autogenous mesenchymal stem cells to physeal defects: an experimental study in rabbits. Prevention of bone bridge formation using transplantation of the autogenous mesenchymal stem cells to physeal defects: an experimental study in rabbits. (en)
skos:notation	RIV/00216224:14110/07:00024223!RIV10-MZ0-14110___
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(1ET400110403), P(2B06130), P(NR8483), Z(AV0Z50390512)
http://linked.open...iv/cisloPeriodika	1
http://linked.open...vai/riv/dodaniDat	2010
http://linked.open...aciTvurceVysledku	Gál, Petr Kecová, Alexandra Nečas, Alois Křen, L. Krupa, Petr Plánka, Ladislav
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Lékařská fakulta
http://linked.open...dnocenehoVysledku	444030
http://linked.open...ai/riv/idVysledku	RIV/00216224:14110/07:00024223
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	growth plate injury; physis; growth arrest; limb deformity (en)
http://linked.open.../riv/klicoveSlovo	growth arrest growth plate injury limb deformity physis
http://linked.open...odStatuVydavatele	CZ - Česká republika
http://linked.open...ontrolniKodProRIV	[0CC91E5E5027]
http://linked.open...i/riv/nazevZdroje	ACTA VET.
http://linked.open...in/vavai/riv/obor	FI
http://linked.open...ichTvurcuVysledku	6 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...vavai/riv/projekt	Protein computer modeling and molecular dynamics simulation The use of the stem cells in growth plate injury treatment - experimental study Synthesis of new biomaterials and preparation of stem cell derived cells, and their aplications in for the treatment of diseases affecting human tissues derived from mesoderm: cartilage, bone, ligament and meniscus.
http://linked.open...UplatneniVysledku	2007
http://linked.open...v/svazekPeriodika	76
http://linked.open...iv/tvurceVysledku	Nečas, Alois Křen, Leoš Krupa, Petr Gál, Petr Plánka, Ladislav Kecová, Alexandra
http://linked.open...ain/vavai/riv/wos	000248084700013
http://linked.open...n/vavai/riv/zamer	Molekulární, buněčné a systémové mechanizmy závažných onemocnění lidského organizmu, jejich diagnostika, terapie a farmakoterapie
issn	0001-7213
number of pages	11 (xsd:int)
http://localhost/t...ganizacniJednotka	14110

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