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rdf:type
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Description
| - Background: Apoptosis plays an important role in normal and malignant lymphopoiesis. Therefore signaling pathways participating in this process are intensively investigated to find their crucial molecules suitable for development and application of new antineoplastic agents. Aims: Based on results of our previous studies and literature search, we selected 9 molecules which play an important role in survival of malignant cells to validate their impact for prediction of outcome in DLBCL. Methods and materials: We studied 46 patients with primary DLBCL.The group consisted of 29 men and 27 women with a median age of 59 years (range, 24-79). Advanced stage (III/IV) was observed in 24 cases (52%) and the distribution according to the IPI was as follows: low risk, 20 cases (44%); low/intermediate risk, 12 (26%); high/intermediate risk 9 (19%); and high risk, 5 (11%).
- Background: Apoptosis plays an important role in normal and malignant lymphopoiesis. Therefore signaling pathways participating in this process are intensively investigated to find their crucial molecules suitable for development and application of new antineoplastic agents. Aims: Based on results of our previous studies and literature search, we selected 9 molecules which play an important role in survival of malignant cells to validate their impact for prediction of outcome in DLBCL. Methods and materials: We studied 46 patients with primary DLBCL.The group consisted of 29 men and 27 women with a median age of 59 years (range, 24-79). Advanced stage (III/IV) was observed in 24 cases (52%) and the distribution according to the IPI was as follows: low risk, 20 cases (44%); low/intermediate risk, 12 (26%); high/intermediate risk 9 (19%); and high risk, 5 (11%). (en)
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Title
| - THE IMPACT OF SELECTED CELL SURVIVAL REGULATORS (OF AKT-2, BCL-2, CD29, PKC-DELTA AND SURVIVIN) ON PREDICTION OF CLINICAL OUTCOME IN DIFFUSE LARGE B-CELL LYMPHOMA (DLBCL)
- THE IMPACT OF SELECTED CELL SURVIVAL REGULATORS (OF AKT-2, BCL-2, CD29, PKC-DELTA AND SURVIVIN) ON PREDICTION OF CLINICAL OUTCOME IN DIFFUSE LARGE B-CELL LYMPHOMA (DLBCL) (en)
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skos:prefLabel
| - THE IMPACT OF SELECTED CELL SURVIVAL REGULATORS (OF AKT-2, BCL-2, CD29, PKC-DELTA AND SURVIVIN) ON PREDICTION OF CLINICAL OUTCOME IN DIFFUSE LARGE B-CELL LYMPHOMA (DLBCL)
- THE IMPACT OF SELECTED CELL SURVIVAL REGULATORS (OF AKT-2, BCL-2, CD29, PKC-DELTA AND SURVIVIN) ON PREDICTION OF CLINICAL OUTCOME IN DIFFUSE LARGE B-CELL LYMPHOMA (DLBCL) (en)
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skos:notation
| - RIV/00216224:14110/07:00019098!RIV10-MZ0-14110___
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/00216224:14110/07:00019098
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - Akt; DLBCL; Prognostic factor; Survivin (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
| - Haematologica/the hematology journal
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...vavai/riv/projekt
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Radová, Lenka
- Vášová, Ingrid
- Svoboda, Marek
- Berkovcová, Jitka
- Fabian, Pavel
- Klabusay, Martin
- Nenutil, Rudolf
- Rejthar, Aleš
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issn
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number of pages
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http://localhost/t...ganizacniJednotka
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