About: Relationship between parameters of cell-mediated immunity, oxidative stress and head and neck squamous cell carcinoma

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About: Relationship between parameters of cell-mediated immunity, oxidative stress and head and neck squamous cell carcinoma Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Oxidative stress, alterations in host immunity and inflammation may contribute to genesis and progression of head and neck squamous cell carcinoma (HNSCC). We investigated relationships between malondialdehyde (MDA) as a marker of lipid peroxidation and parameters of activated macrophages, i.e. tumor necrosis factor alpha as a marker of inflammation and neopterin as a marker of cell-mediated immunity and clinical stage of HNSCC. Our results confirm the role of activated macrophages and the cellular immune system in HNSCC. In patients with activated T-lymphocytes, levels of TNF alpha inversely reflected the prognosis of disease. Although production of MDA in HNSCC patients is normal, it seems that activated T-lymphocytes contribute to lipid peroxidation. Oxidative stress, alterations in host immunity and inflammation may contribute to genesis and progression of head and neck squamous cell carcinoma (HNSCC). We investigated relationships between malondialdehyde (MDA) as a marker of lipid peroxidation and parameters of activated macrophages, i.e. tumor necrosis factor alpha as a marker of inflammation and neopterin as a marker of cell-mediated immunity and clinical stage of HNSCC. Our results confirm the role of activated macrophages and the cellular immune system in HNSCC. In patients with activated T-lymphocytes, levels of TNF alpha inversely reflected the prognosis of disease. Although production of MDA in HNSCC patients is normal, it seems that activated T-lymphocytes contribute to lipid peroxidation. (en)
Title	Relationship between parameters of cell-mediated immunity, oxidative stress and head and neck squamous cell carcinoma Relationship between parameters of cell-mediated immunity, oxidative stress and head and neck squamous cell carcinoma (en)
skos:prefLabel	Relationship between parameters of cell-mediated immunity, oxidative stress and head and neck squamous cell carcinoma Relationship between parameters of cell-mediated immunity, oxidative stress and head and neck squamous cell carcinoma (en)
skos:notation	RIV/00216224:14110/07:00019043!RIV10-MZ0-14110___
http://linked.open...avai/riv/aktivita	P
http://linked.open...avai/riv/aktivity	P(NR7996), P(NR9200)
http://linked.open...vai/riv/dodaniDat	2010
http://linked.open...aciTvurceVysledku	Salzman, Richard Tomandl, Josef Kostřica, Rom Horáková, Zuzana
http://linked.open.../riv/druhVysledku	D - Článek ve sborníku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Lékařská fakulta
http://linked.open...dnocenehoVysledku	447187
http://linked.open...ai/riv/idVysledku	RIV/00216224:14110/07:00019043
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	head and neck cell carcinoma; oxidative stress; cell-mediated immunity (en)
http://linked.open.../riv/klicoveSlovo	head and neck cell carcinoma oxidative stress cell-mediated immunity
http://linked.open...ontrolniKodProRIV	[3D4283909EC6]
http://linked.open...v/mistoKonaniAkce	Bratislava
http://linked.open...i/riv/mistoVydani	Bratislava
http://linked.open...i/riv/nazevZdroje	Book of abstracts from the conference Synthetic and natural compounds in cancer therapy and prevention.
http://linked.open...in/vavai/riv/obor	CE
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...vavai/riv/projekt	Dynamics of oxidative stress during oncotherapy and prognosis of patients with head and neck carcinomas Antioxidative enzymes polymorphisms and membranous tracheobronchitis as serious complication after tracheotomy
http://linked.open...UplatneniVysledku	2007
http://linked.open...iv/tvurceVysledku	Horáková, Zuzana Kostřica, Rom Tomandl, Josef Salzman, Richard
http://linked.open...vavai/riv/typAkce	EUR - Evropská
http://linked.open.../riv/zahajeniAkce	2007-03-28 (xsd:date)
number of pages	1 (xsd:int)
http://purl.org/ne...btex#hasPublisher	Mind and Health, civil association
https://schema.org/isbn	978-80-969663-2-5
http://localhost/t...ganizacniJednotka	14110

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