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  • Rozvoj neurogenního a myogenního postižení v rámci neuromuskulárních komplikací kritického stavu: longitudinální histopatologická studie Histopatologická analýza 52 biopsií od 43 dospělých nemocných v kritickém stavu byla zaměřena na průběh polyneuropatie (CIP) a myopatie kritického stavu (CIM). Vzorky získané otevřenou a polootevřenou biopsií byly zpracovány konvenčními histologickými a histopatologickými metodami. Výsledky byly porovnány s neurofyziologickými nálezy a klinickým stavem pacientů. ICM a ICM se rozvinuly krátce po začátku kritického stavu. nejdelší interval mezi začátkem kritického stavu a rozvojem CIM byl 42 dnů, poté byly zaznamenány pouze mírné formy CIP. U 9 nemocných byla biopsie provedena opakovaně a histologický obraz se změnil ve všech případech. Pokud byla opakovaná biospie provedena 11-31 měsíců po první biopsii, všechny myogenní změny vymizely a došlo k normalizaci nálezu (5 případů) nebo byly přítomny známky perizistentní neurogenní léze. Na druhé straně, elektrofyziologické (cs)
  • Histopathological analysis of 52 biopsies from 43 adult critically ill patients was focused on the course of critically ill patients with intensive care polyneuropathy (ICP) or myopathy (ICM). Needle or open biopsies were processed using a set of conventional histological and histochemical methods. The results were compared with neurophysiologic findings and the clinical state of the patients. ICM and ICP develop soon after the beginning of the disease. The longest interval between the onset of the disease and findings of necrotizing myopathy (MN) was 6 weeks (42 days) after the beginning of the disease, thereafter only ICP of mild forms of ICM were recorded. In nine patients, the biopsy examination was repeated and the histological picture of the lesion changed in all cases. When the second biopsy was performed 11-31 months after the 1st one (7 samples), all myogenic features i.e. picture of simple or necrotizing myopathy disappeared and either recovery with normal histopathological finding (five pat
  • Histopathological analysis of 52 biopsies from 43 adult critically ill patients was focused on the course of critically ill patients with intensive care polyneuropathy (ICP) or myopathy (ICM). Needle or open biopsies were processed using a set of conventional histological and histochemical methods. The results were compared with neurophysiologic findings and the clinical state of the patients. ICM and ICP develop soon after the beginning of the disease. The longest interval between the onset of the disease and findings of necrotizing myopathy (MN) was 6 weeks (42 days) after the beginning of the disease, thereafter only ICP of mild forms of ICM were recorded. In nine patients, the biopsy examination was repeated and the histological picture of the lesion changed in all cases. When the second biopsy was performed 11-31 months after the 1st one (7 samples), all myogenic features i.e. picture of simple or necrotizing myopathy disappeared and either recovery with normal histopathological finding (five pat (en)
Title
  • Development of neurogenic and myogenic conditions in critical illness neuromuscular disorders: follow-up histopathological study
  • Development of neurogenic and myogenic conditions in critical illness neuromuscular disorders: follow-up histopathological study (en)
  • Rozvoj neurogenního a myogenního postižení v rámci neuromuskulárních komplikací kritického stavu: longitudinální histopatologická studie (cs)
skos:prefLabel
  • Development of neurogenic and myogenic conditions in critical illness neuromuscular disorders: follow-up histopathological study
  • Development of neurogenic and myogenic conditions in critical illness neuromuscular disorders: follow-up histopathological study (en)
  • Rozvoj neurogenního a myogenního postižení v rámci neuromuskulárních komplikací kritického stavu: longitudinální histopatologická studie (cs)
skos:notation
  • RIV/00216224:14110/06:00018054!RIV07-MSM-14110___
http://linked.open.../vavai/riv/strany
  • 702
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • Z(MSM0021622404)
http://linked.open...iv/cisloPeriodika
  • Suppl
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 471310
http://linked.open...ai/riv/idVysledku
  • RIV/00216224:14110/06:00018054
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • Critical illness; polyneuropathy; myopathy; histopatological findings (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV
  • [E94E6849EA88]
http://linked.open...i/riv/nazevZdroje
  • Neuromuscular Disorders
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 16
http://linked.open...iv/tvurceVysledku
  • Bednařík, Josef
  • Lukáš, Zdeněk
  • Maňák, Jan
  • Schreiber, M.
http://linked.open...n/vavai/riv/zamer
issn
  • 0968-8966
number of pages
http://localhost/t...ganizacniJednotka
  • 14110
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