About: Association of eNOS gene polymorphisms T-786C and G894T with blood pressure variability

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Association of eNOS gene polymorphisms T-786C and G894T with blood pressure variability Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Association of single nucleotide polymorphisms (SNPs) T-786C and G894T in gene encoding eNOS with blood pressure variability (BPV) in man was evaluated. Systolic and diastolic blood pressure variability in relative and absolute units were determined in 129 healthy subjects by spectral method as spectral power at the frequency of 0.1 Hz. Genotypes were detected by means of polymerase chain reaction and restriction analysis. Carriers of less frequent alleles showed significantly greater BPV comparing more frequent alleles homozygotes. The determined SNPs were in linkage disequilibrium. Carriers of genotype CC (for T-786C) with TT (for G894T) displayed significantly greater BPV compared to carriers of other genotype combinations. We found significant associations of T-786C and G894T polymorphisms in gene encoding eNOS with systolic and diastolic blood pressure variability. Less frequent alleles of T-786C and G894T in gene encoding eNOS are associated with increased systolic and diastolic BPV. Association of single nucleotide polymorphisms (SNPs) T-786C and G894T in gene encoding eNOS with blood pressure variability (BPV) in man was evaluated. Systolic and diastolic blood pressure variability in relative and absolute units were determined in 129 healthy subjects by spectral method as spectral power at the frequency of 0.1 Hz. Genotypes were detected by means of polymerase chain reaction and restriction analysis. Carriers of less frequent alleles showed significantly greater BPV comparing more frequent alleles homozygotes. The determined SNPs were in linkage disequilibrium. Carriers of genotype CC (for T-786C) with TT (for G894T) displayed significantly greater BPV compared to carriers of other genotype combinations. We found significant associations of T-786C and G894T polymorphisms in gene encoding eNOS with systolic and diastolic blood pressure variability. Less frequent alleles of T-786C and G894T in gene encoding eNOS are associated with increased systolic and diastolic BPV. (en)
Title	Association of eNOS gene polymorphisms T-786C and G894T with blood pressure variability Association of eNOS gene polymorphisms T-786C and G894T with blood pressure variability (en)
skos:prefLabel	Association of eNOS gene polymorphisms T-786C and G894T with blood pressure variability Association of eNOS gene polymorphisms T-786C and G894T with blood pressure variability (en)
skos:notation	RIV/00216224:14110/06:00017819!RIV10-MSM-14110___
http://linked.open...avai/riv/aktivita	Z
http://linked.open...avai/riv/aktivity	Z(MSM0021622402)
http://linked.open...vai/riv/dodaniDat	2010
http://linked.open...aciTvurceVysledku	Jíra, Miroslav Izakovičová-Hollá, Lydie Závodná, Eva Fišer, Bohumil Vašků, Anna Honzíková, Nataša Nováková, Zuzana Znojil, Vladimír
http://linked.open.../riv/druhVysledku	O - Ostatní výsledky nezařaditelné do žádného z výše uvedených druhů výsledku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Lékařská fakulta
http://linked.open...dnocenehoVysledku	466191
http://linked.open...ai/riv/idVysledku	RIV/00216224:14110/06:00017819
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	blood pressure variability; spectral analysis; nitric oxide synthase; nitric oxide; polymorphism (en)
http://linked.open.../riv/klicoveSlovo	spectral analysis nitric oxide synthase polymorphism blood pressure variability nitric oxide
http://linked.open...ontrolniKodProRIV	[7C22B610A6A8]
http://linked.open...in/vavai/riv/obor	ED
http://linked.open...ichTvurcuVysledku	8 (xsd:int)
http://linked.open...cetTvurcuVysledku	8 (xsd:int)
http://linked.open...UplatneniVysledku	2006
http://linked.open...iv/tvurceVysledku	Fišer, Bohumil Honzíková, Nataša Izakovičová-Hollá, Lydie Jíra, Miroslav Nováková, Zuzana Vašků, Anna Závodná, Eva Znojil, Vladimír
http://linked.open...n/vavai/riv/zamer	Early diagnostics and treatment of cardiovascular diseases
http://localhost/t...ganizacniJednotka	14110

Faceted Search & Find service v1.16.118 as of Jun 21 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 58 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software