About: Exoproducts of the strain Escherichia coli H22 inhibiting some enteric pathogens both in vitro and in vivo.

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About: Exoproducts of the strain Escherichia coli H22 inhibiting some enteric pathogens both in vitro and in vivo. Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	AIMS: The antagonistic activity of the Escherichia coli strain H22 against enteric bacteria was studied both in vitro and in vivo. METHODS AND RESULTS: In vitro, bacterial strains belonging to seven of nine genera of the family Enterobacteriaceae (Enterobacter, Escherichia, Klebsiella, Morganella, Salmonella, Shigella and Yersinia) were inhibited by the strain H22. Six days after simultaneous oral inoculation in germ-free mice, E. coli strain H22 reduced the faecal population of Shigella flexneri 4 to undetectable levels (P < 0.05). In ex vivo assay, inhibitory zones against Sh. flexneri 4 were observed around faecal samples from mice inoculated with E. coli strain H22. The in vitro inhibition of Sh. flexneri 4 was shown to be mediated by microcin C7. In addition to microcin C7, strain H22 was shown to produce aerobactin, new variants of colicins E1 and Ib, and bacteriophage particles with morphology similar to the phages of the family Myoviridae. CONCLUSIONS: Altogether, the properties of E. AIMS: The antagonistic activity of the Escherichia coli strain H22 against enteric bacteria was studied both in vitro and in vivo. METHODS AND RESULTS: In vitro, bacterial strains belonging to seven of nine genera of the family Enterobacteriaceae (Enterobacter, Escherichia, Klebsiella, Morganella, Salmonella, Shigella and Yersinia) were inhibited by the strain H22. Six days after simultaneous oral inoculation in germ-free mice, E. coli strain H22 reduced the faecal population of Shigella flexneri 4 to undetectable levels (P < 0.05). In ex vivo assay, inhibitory zones against Sh. flexneri 4 were observed around faecal samples from mice inoculated with E. coli strain H22. The in vitro inhibition of Sh. flexneri 4 was shown to be mediated by microcin C7. In addition to microcin C7, strain H22 was shown to produce aerobactin, new variants of colicins E1 and Ib, and bacteriophage particles with morphology similar to the phages of the family Myoviridae. CONCLUSIONS: Altogether, the properties of E. (en)
Title	Exoproducts of the strain Escherichia coli H22 inhibiting some enteric pathogens both in vitro and in vivo. Exoproducts of the strain Escherichia coli H22 inhibiting some enteric pathogens both in vitro and in vivo. (en)
skos:prefLabel	Exoproducts of the strain Escherichia coli H22 inhibiting some enteric pathogens both in vitro and in vivo. Exoproducts of the strain Escherichia coli H22 inhibiting some enteric pathogens both in vitro and in vivo. (en)
skos:notation	RIV/00216224:14110/06:00016056!RIV10-GA0-14110___
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA310/03/1091), Z(MSM0021622415)
http://linked.open...iv/cisloPeriodika	4
http://linked.open...vai/riv/dodaniDat	2010
http://linked.open...aciTvurceVysledku	Šmarda, Jan Šmajs, David
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Lékařská fakulta
http://linked.open...dnocenehoVysledku	475015
http://linked.open...ai/riv/idVysledku	RIV/00216224:14110/06:00016056
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	bacteriophage; col-plasmid; colicin; Escherichia coli; growth inhibition; microcin (en)
http://linked.open.../riv/klicoveSlovo	colicin microcin growth inhibition Escherichia coli bacteriophage col-plasmid
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[2C71F7681FA3]
http://linked.open...i/riv/nazevZdroje	Journal of Applied Microbiology
http://linked.open...in/vavai/riv/obor	EE
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	7 (xsd:int)
http://linked.open...vavai/riv/projekt	Mapping of the colicin route to the sensitive and immune bacterium: studies on colicin-receptor and colicin-immunity protein interaction
http://linked.open...UplatneniVysledku	2006
http://linked.open...v/svazekPeriodika	100
http://linked.open...iv/tvurceVysledku	Šmarda, Jan Šmajs, David Chartone-Souza, E. Cursino, L. Nardi, R. M. D. Nascimento, A. M. A. Nicoli, J. R.
http://linked.open...ain/vavai/riv/wos	000236024400023
http://linked.open...n/vavai/riv/zamer	Molecular basis of cell and tissue regulations
issn	1364-5072
number of pages	9 (xsd:int)
http://localhost/t...ganizacniJednotka	14110

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