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  • The model of rat ventricular myocyte was used to investigate the physiological consequences of acidosis. The results of simulations were in agreement with experimental observations and showed that acidosis causes increase of intracellular Na+, intracellular Ca2+ and amplitude of Cai transients.
  • The model of rat ventricular myocyte was used to investigate the physiological consequences of acidosis. The results of simulations were in agreement with experimental observations and showed that acidosis causes increase of intracellular Na+, intracellular Ca2+ and amplitude of Cai transients. (en)
Title
  • A Computational model of the effects of acidosis on intracellular Ca2+ in rat ventricular myocytes
  • A Computational model of the effects of acidosis on intracellular Ca2+ in rat ventricular myocytes (en)
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  • A Computational model of the effects of acidosis on intracellular Ca2+ in rat ventricular myocytes
  • A Computational model of the effects of acidosis on intracellular Ca2+ in rat ventricular myocytes (en)
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  • RIV/00216224:14110/04:00030848!RIV10-MSM-14110___
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  • Z(MSM 141100004)
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  • 552866
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  • RIV/00216224:14110/04:00030848
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  • cardiac cell; acidosis; quantitative modelling (en)
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  • [83124BA93CFC]
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  • Orchard, Clive
  • Pásek, Michal
  • Clayton, Rychard
  • Langham, Elise
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  • 14110
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