About: Cardiotoxicity and baroreflex sensitivity in children treated with anthracycline for leukaemia

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About: Cardiotoxicity and baroreflex sensitivity in children treated with anthracycline for leukaemia Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Kardiotoxicita antracyklinových antibiotik používaných v léčbě leukémie je dobře známa. Bylo pozorováno snížení krevního tlaku (systolického i diastolického), které přetrvává i několik let po této léčbě. Zajímal nás vztah kardiotoxicity a regulačních mechanismů krevního tlaku. Echokardiograficky jmse stanovili ejekční frakci (EF). Signifikantně nižší hodnoty systolického krevního tlaku u skupiny pacientů s nízkou EF oproti skupině s vyššími hodnotami EF ukazuje na vztah mezi kardiotoxicitou a regulací krevního tlaku. Citlivost baroreflexu není ovlivněna. (cs) Cardiotoxicity of anthracycline used for leukemia treatment is well known. Recently we observed decrease of systolic (SBP) and diastolic pressure (DBP) after the anthracycline treatment, which is seen still after several years. The link between cardiotoxicity and the blood pressure regulation was examined in the present study. Significant decrease of SBP in patients with low EF indicates a link between blood pressure decrease and anthracycline cardiotoxicity. Baroreflex sensitivity is not influenced. Cardiotoxicity of anthracycline used for leukemia treatment is well known. Recently we observed decrease of systolic (SBP) and diastolic pressure (DBP) after the anthracycline treatment, which is seen still after several years. The link between cardiotoxicity and the blood pressure regulation was examined in the present study. Significant decrease of SBP in patients with low EF indicates a link between blood pressure decrease and anthracycline cardiotoxicity. Baroreflex sensitivity is not influenced. (en)
Title	Kardiotoxicita a citlivost baroreflexu u dětí léčených antracykliny pro leukémii (cs) Cardiotoxicity and baroreflex sensitivity in children treated with anthracycline for leukaemia Cardiotoxicity and baroreflex sensitivity in children treated with anthracycline for leukaemia (en)
skos:prefLabel	Kardiotoxicita a citlivost baroreflexu u dětí léčených antracykliny pro leukémii (cs) Cardiotoxicity and baroreflex sensitivity in children treated with anthracycline for leukaemia Cardiotoxicity and baroreflex sensitivity in children treated with anthracycline for leukaemia (en)
skos:notation	RIV/00216224:14110/04:00010839!RIV08-MSM-14110___
http://linked.open.../vavai/riv/strany	51P
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(NR8006), Z(MSM 141100004)
http://linked.open...iv/cisloPeriodika	5
http://linked.open...vai/riv/dodaniDat	2008
http://linked.open...aciTvurceVysledku	Závodná, Eva Fišer, Bohumil Elbl, Lubomír Hrstková, Hana Honzíková, Nataša Nováková, Zuzana
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Lékařská fakulta
http://linked.open...dnocenehoVysledku	556855
http://linked.open...ai/riv/idVysledku	RIV/00216224:14110/04:00010839
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	cardiotoxicity; anthracycline; baroreflex sensitivity; children; leukaemia (en)
http://linked.open.../riv/klicoveSlovo	baroreflex sensitivity children anthracycline cardiotoxicity leukaemia
http://linked.open...odStatuVydavatele	CZ - Česká republika
http://linked.open...ontrolniKodProRIV	[A8A0FB193B7C]
http://linked.open...i/riv/nazevZdroje	Physiological Research
http://linked.open...in/vavai/riv/obor	ED
http://linked.open...ichTvurcuVysledku	6 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...vavai/riv/projekt	Automonous circulations functions,myocard and cardiorespiratory functions in children and adolescents after malignancy treatment.
http://linked.open...UplatneniVysledku	2004
http://linked.open...v/svazekPeriodika	53
http://linked.open...iv/tvurceVysledku	Fišer, Bohumil Honzíková, Nataša Hrstková, Hana Nováková, Zuzana Závodná, Eva Elbl, Lubomír
http://linked.open...n/vavai/riv/zamer	http://linked.opendata.cz/resource/domain/vavai/zamer/MSM%20141100004
issn	0862-8408
number of pages	1 (xsd:int)
http://localhost/t...ganizacniJednotka	14110

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